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MIRIKIZUMAB
Z7HVY03PHP
US Approved Rx (2023)
First approved in 2023
General
Record Details
Variant Concepts
1
Names
7
Classification
2
Identifiers
7
Subunits
4
Disulfide Links
16
Glycosylation
2
Relationships
2
Active Moiety
1
Characteristic Attributes
2
MIRIKIZUMAB
Z7HVY03PHP
US Approved Rx (2023)
First approved in 2023
General
Approval Year
2023
455
Record Details
Substance Class
Protein
Protein Type
MONOCLONAL ANTIBODY
Protein Sub Type
IGG4
Sequence Origin
HUMANIZED MOUSE
Sequence Type
COMPLETE
Record UNII
Z7HVY03PHP
Record Status
Validated (UNII)
Record Version
30
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Related Record
Type
Related Record
Type
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Names
7
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entries
Name
Type
Language
Name
Type
Language
MIRIKIZUMAB
Official Name
English
LY3074828
Code
English
MIRIKIZUMAB [USAN]
Common Name
English
LY-3074828
Code
English
mirikizumab [INN]
Common Name
English
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Classification
2
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Designated
ORPHAN DRUG
Designated
Treatment of ulcerative colitis in pediatric patients
FDA ORPHAN DRUG
577817
Designated
ORPHAN DRUG
Designated
Treatment of pediatric Crohn's disease
FDA ORPHAN DRUG
584617
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Identifiers
7
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Code System
Code
Type
Description
Code System
Code
Type
Description
FDA UNII
Z7HVY03PHP
PRIMARY
NCI_THESAURUS
C170182
PRIMARY
USAN
DE-114
PRIMARY
CAS
1884201-71-1
PRIMARY
INN
10657
PRIMARY
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Subunits
4
Disulfide Links
16
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From
To
From
To
1_22
1_96
1_129
3_214
1_142
1_198
1_221
2_221
1_224
2_224
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Glycosylation
2
Glycosylation Type
MAMMALIAN
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Glycosylation Link Type
Site
Glycosylation Link Type
Site
N
1_292
N
2_292
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Relationships
2
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Related Record
Type
Details
Related Record
Type
Details
5OL0CTF85B
INTERLEUKIN-23 SUBUNIT ALPHA
TARGET -> INHIBITOR
Mirikizumab-MRKZ
SUB_CONCEPT->SUBSTANCE
Amount:
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Active Moiety
1
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Related Record
Type
Details
Related Record
Type
Details
Z7HVY03PHP
MIRIKIZUMAB
ACTIVE MOIETY
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Characteristic Attributes
2
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Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Molecular Formula
CHEMICAL
ESTIMATED
C6380H9826N1686O2004S48
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
ESTIMATED 144000 Da (average)
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