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Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 14:43:50 UTC 2023
Edited
by admin
on Sat Dec 16 14:43:50 UTC 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
Z6Z6IVE7W4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Petosemtamab
INN  
Official Name English
MCLA158
Code English
Immunoglobulin G1 [361-lysine, 376-lysine], anti-(human leucine-rich repeat-containing G protein-coupled receptor LGR5) (human monoclonal MCLA-158 γ1-chain), disulfide with human monoclonal MCLA-158 κ-chain, (236→229'), (239→232')-bis(disulfide) wi
Common Name English
PETOSEMTAMAB [USAN]
Common Name English
petosemtamab [INN]
Common Name English
Petosemtamab [WHO-DD]
Common Name English
MCLA-158
Code English
immunoglobulin G1-kappa, anti-[Homo sapiens EGFR (epidermal growth factor receptor, receptor tyrosine-protein kinase erbB-1, ERBB1, HER1, HER-1, ERBB)], and anti-[Homo sapiens LGR5 (leucine rich repeat containing G protein-coupled receptor 5, G protein-c
Common Name English
Code System Code Type Description
USAN
KL-118
Created by admin on Sat Dec 16 14:43:50 UTC 2023 , Edited by admin on Sat Dec 16 14:43:50 UTC 2023
PRIMARY
NCI_THESAURUS
C174952
Created by admin on Sat Dec 16 14:43:50 UTC 2023 , Edited by admin on Sat Dec 16 14:43:50 UTC 2023
PRIMARY
CAS
2213450-26-9
Created by admin on Sat Dec 16 14:43:50 UTC 2023 , Edited by admin on Sat Dec 16 14:43:50 UTC 2023
PRIMARY
INN
11136
Created by admin on Sat Dec 16 14:43:50 UTC 2023 , Edited by admin on Sat Dec 16 14:43:50 UTC 2023
PRIMARY
FDA UNII
Z6Z6IVE7W4
Created by admin on Sat Dec 16 14:43:50 UTC 2023 , Edited by admin on Sat Dec 16 14:43:50 UTC 2023
PRIMARY
From To
1_22 1_96
1_147 1_203
1_223 3_214
1_229 2_236
1_232 2_239
1_264 1_324
1_370 1_428
2_22 2_96
2_154 2_210
2_230 4_214
2_271 2_331
2_377 2_435
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
2_101 2_106
Glycosylation Type MAMMALIAN, AFUCOSYLATED
Glycosylation Link Type Site
N 1_300
N 2_307
Related Record Type Details
Petosemtamab
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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