Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C9H12FN3O4 |
| Molecular Weight | 244.2102 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2[18F]
InChI
InChIKey=NVZFZMCNALTPBY-OEXKADLXSA-N
InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6+,7-,8-/m1/s1/i10-1
| Molecular Formula | C9H12FN3O4 |
| Molecular Weight | 244.2102 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Design, synthesis, and antiviral properties of 4'-substituted ribonucleosides as inhibitors of hepatitis C virus replication: the discovery of R1479. | 2007-05-01 |
|
| Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication. | 2006 |
|
| Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication. | 2005-08-25 |
|
| Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system. | 2005-03-01 |
|
| Synthesis of some 2'-fluoro-2'-deoxy-3'-C-ethynyl and 3'-C-vinyl-beta-D-lyxofuranosyl nucleosides. | 2005 |
|
| Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine. | 2004-02 |
|
| Measurement of the anti-cancer agent gemcitabine in human plasma by high-performance liquid chromatography. | 2003-02-25 |
|
| Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides. | 1979-01 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:47:36 GMT 2025
by
admin
on
Mon Mar 31 21:47:36 GMT 2025
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| Record UNII |
Z5NYK64WXC
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| Record Status |
Validated (UNII)
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| Record Version |
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1052670-04-8
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71587916
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Z5NYK64WXC
Created by
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DTXSID90147039
Created by
admin on Mon Mar 31 21:47:36 GMT 2025 , Edited by admin on Mon Mar 31 21:47:36 GMT 2025
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NON-LABELED -> LABELED |
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TARGET -> SUBSTRATE |
Enabled visualization of lymphoid organs and was sensitive to localized immune activation.
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ACTIVE MOIETY |
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