Avitotamig

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 11:58:13 GMT 2025` Edited by `admin` on `Wed Apr 02 11:58:13 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	Z32GG78KKJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

YMS-5A

Preferred Name

English

Avitotamig

Official Name

English

YMS-5A (CD33XCD3 BISPECIFIC ANTIBODY)

Code

English

Immunoglobulin G1, anti-(human sialic acid-binding Ig-like lectin 3)(human-Mus musculus ?-chain) fusion protein with peptide linker (TS(GGGGS)3) fusion protein with immunoglobulin anti-(human CD3 antigen ?-chain) (human-Mus musculus clone OKT3 single-cha

Common Name

English

avitotamig [INN]

Common Name

English

AVITOTAMIG [USAN]

Common Name

English

Code System Code Type Description

CAS

2577961-36-3

Created by admin on Wed Apr 02 11:58:13 GMT 2025 , Edited by admin on Wed Apr 02 11:58:13 GMT 2025

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FDA UNII

Z32GG78KKJ

Created by admin on Wed Apr 02 11:58:13 GMT 2025 , Edited by admin on Wed Apr 02 11:58:13 GMT 2025

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NCI_THESAURUS

C204138

Created by admin on Wed Apr 02 11:58:13 GMT 2025 , Edited by admin on Wed Apr 02 11:58:13 GMT 2025

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USAN

LM-88

Created by admin on Wed Apr 02 11:58:13 GMT 2025 , Edited by admin on Wed Apr 02 11:58:13 GMT 2025

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INN

13055

Created by admin on Wed Apr 02 11:58:13 GMT 2025 , Edited by admin on Wed Apr 02 11:58:13 GMT 2025

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SMS_ID

300000053868

Created by admin on Wed Apr 02 11:58:13 GMT 2025 , Edited by admin on Wed Apr 02 11:58:13 GMT 2025

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From	To
3_231	4_231
3_228	4_228
2_213	4_222
1_213	3_222
4_369	4_427
4_263	4_323
4_146	4_202
4_22	4_96
3_369	3_427
3_263	3_323
3_146	3_202
3_22	3_96
2_402	2_466
1_402	1_466
2_274	2_478
2_252	2_326
2_133	2_193
2_23	2_88
1_274	1_478
1_252	1_326
1_133	1_193
1_23	1_88

Related Record Type Details


					Z32GG78KKJ

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[3_449] [4_449]			Amount:	LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[3_1] [4_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL