PALUPIPRANT

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H18F5N3O4
Molecular Weight	483.388
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H](NC(=O)C1=C(OC2=CC=CC(=C2)C(F)(F)F)N(C)N=C1C(F)F)C3=CC=C(C=C3)C(O)=O

InChI

InChIKey=MKLKAQMPKHNQPR-NSHDSACASA-N

InChI=1S/C22H18F5N3O4/c1-11(12-6-8-13(9-7-12)21(32)33)28-19(31)16-17(18(23)24)29-30(2)20(16)34-15-5-3-4-14(10-15)22(25,26)27/h3-11,18H,1-2H3,(H,28,31)(H,32,33)/t11-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C22H18F5N3O4
Molecular Weight	483.388
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Prostanoid EP4 receptor 12 Target ID: CHEMBL1836 Sources: https://adisinsight.springer.com/drugs/800043211 \| DOI: 10.1158/1538-7445.AM2015-275	Antagonist 2849		17.0 nM [Ki]

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:39:35 GMT 2025` Edited by `admin` on `Mon Mar 31 22:39:35 GMT 2025`
Record UNII	YWY620GU8I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PALUPIPRANT

Official Name

English

E 7046 [WHO-DD]

Preferred Name

English

BENZOIC ACID, 4-((1S)-1-(((3-(DIFLUOROMETHYL)-1-METHYL-5-(3-(TRIFLUOROMETHYL)PHENOXY)-1H-PYRAZOL-4-YL)CARBONYL)AMINO)ETHYL)-

Systematic Name

English

4-((1S)-1-(((3-(DIFLUOROMETHYL)-1-METHYL-5-(3-(TRIFLUOROMETHYL)PHENOXY)-1H-PYRAZOL-4-YL)CARBONYL)AMINO)ETHYL)BENZOIC ACID

Systematic Name

English

ER-886046

Common Name

English

ER 886046 [WHO-DD]

Common Name

English

palupiprant [INN]

Common Name

English

Code System Code Type Description

INN

12035