TAS-103 FREE BASE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H19N3O2
Molecular Weight	333.3838
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)CCNC1=C2C(=O)C3=CC=CC=C3C2=C4C=CC(O)=CC4=N1

InChI

InChIKey=ROWSTIYZUWEOMM-UHFFFAOYSA-N

InChI=1S/C20H19N3O2/c1-23(2)10-9-21-20-18-17(13-5-3-4-6-14(13)19(18)25)15-8-7-12(24)11-16(15)22-20/h3-8,11,24H,9-10H2,1-2H3,(H,21,22)

HIDE SMILES / InChI

Molecular Formula	C20H19N3O2
Molecular Weight	333.3838
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
DNA topoisomerase I 59 Target ID: CHEMBL1781 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10100595	Inhibitor 8297		2.0 µM [IC50]
DNA topoisomerase II 66 Target ID: CHEMBL2094255 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10100595	Inhibitor 8297		6.5 µM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:14:02 GMT 2023` Edited by `admin` on `Sat Dec 16 11:14:02 GMT 2023`
Record UNII	YVC96489QV
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TAS-103 FREE BASE

Common Name

English

J812.866I

Code

English

7H-INDENO(2,1-C)QUINOLIN-7-ONE, 6-((2-(DIMETHYLAMINO)ETHYL)AMINO)-3-HYDROXY-

Systematic Name

English

3-HYDROXY-6-((2-(DIMETHYLAMINO)ETHYL)AMINO)-7H-INDENO(2,1-C)QUINOLIN-7-ONE

Systematic Name

English

Code System Code Type Description

PUBCHEM

135413533

Created by admin on Sat Dec 16 11:14:02 GMT 2023 , Edited by admin on Sat Dec 16 11:14:02 GMT 2023

PRIMARY

CAS

174634-08-3

Created by admin on Sat Dec 16 11:14:02 GMT 2023 , Edited by admin on Sat Dec 16 11:14:02 GMT 2023

PRIMARY

FDA UNII

YVC96489QV

Created by admin on Sat Dec 16 11:14:02 GMT 2023 , Edited by admin on Sat Dec 16 11:14:02 GMT 2023

PRIMARY

Related Record Type Details


					1X260YUP2P

TAS-103

SALT/SOLVATE -> PARENT

Related Record Type Details


					YVC96489QV

TAS-103 FREE BASE

ACTIVE MOIETY