TAS-103

Cl.Cl.CN(C)CCNC1=C2C(=O)C3=C(C=CC=C3)C2=C4C=CC(O)=CC4=N1

InChIKey=HAYAYGFVSIWSGQ-UHFFFAOYSA-N

InChI=1S/C20H19N3O2.2ClH/c1-23(2)10-9-21-20-18-17(13-5-3-4-6-14(13)19(18)25)15-8-7-12(24)11-16(15)22-20;;/h3-8,11,24H,9-10H2,1-2H3,(H,21,22);2*1H

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
DNA topoisomerase I 60 Target ID: CHEMBL1781 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10100595	Inhibitor 8504		2.0 µM [IC50]
DNA topoisomerase II 66 Target ID: CHEMBL2094255 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10100595	Inhibitor 8504		6.5 µM [IC50]

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:00:56 GMT 2025` Edited by `admin` on `Mon Mar 31 18:00:56 GMT 2025`
Record UNII	1X260YUP2P
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

TAS-103

Common Name

English

BMS-247615

Preferred Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1748