OBRINDATAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 23:33:34 GMT 2025` Edited by `admin` on `Tue Apr 01 23:33:34 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	YE8XXF1SDZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

obrindatamab [INN]

Preferred Name

English

OBRINDATAMAB

Official Name

English

MGD-009

Code

English

Obrindatamab [WHO-DD]

Common Name

English

DUAL-AFFINITY B7-H3/CD3-TARGETED PROTEIN MGD009

Common Name

English

MGD009

Code

English

Code System Code Type Description

FDA UNII

YE8XXF1SDZ

Created by admin on Tue Apr 01 23:33:34 GMT 2025 , Edited by admin on Tue Apr 01 23:33:34 GMT 2025

PRIMARY

INN

11181

Created by admin on Tue Apr 01 23:33:34 GMT 2025 , Edited by admin on Tue Apr 01 23:33:34 GMT 2025

PRIMARY

NCI_THESAURUS

C136983

Created by admin on Tue Apr 01 23:33:34 GMT 2025 , Edited by admin on Tue Apr 01 23:33:34 GMT 2025

PRIMARY

CAS

2069959-72-2

Created by admin on Tue Apr 01 23:33:34 GMT 2025 , Edited by admin on Tue Apr 01 23:33:34 GMT 2025

PRIMARY

SMS_ID

300000008766

Created by admin on Tue Apr 01 23:33:34 GMT 2025 , Edited by admin on Tue Apr 01 23:33:34 GMT 2025

PRIMARY

From	To
1_23	1_88
1_137	1_213
1_283	3_6
1_286	3_9
2_22	2_90
1_318	1_378
1_424	1_482
2_140	2_214
1_243	2_243
3_41	3_101
3_147	3_205

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_354
N	3_77

Related Record Type Details


					961Y201EWR

TARGET->LIGAND

Amount:


					ZLW14X2D30

CD3

TARGET -> ACTIVATOR

Amount:

Related Record Type Details


					YE8XXF1SDZ

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_504] [3_227]	C-TERMINUS			LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL