Ambenoxan is a muscle relaxant. Ambenoxan exerts its effects via an action on brain and/or spinal mechanisms. Ambenoxan has been shown to produce skeletal muscle flaccidity without loss of the righting reflex when administered orally or parenterally to rats, rabbits, dogs and monkeys. The drug is approximately twice as toxic orally as it is subcutaneously, which suggests that the compound is effectively absorbed by the oral route. Ambenoxan may be of value in the treatment of spastic disorders resulting from upper motor neurone damage in the brain or spinal cord, disseminated sclerosis, spastic diplegia and spastic hemiplegia.