Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H12F4N4O3S |
| Molecular Weight | 464.393 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=CC=C(C=C1F)N2C(=S)N(C(=O)C23CCC3)C4=CC(=C(N=C4)C#N)C(F)(F)F
InChI
InChIKey=ICXCBGDFYFFSGX-UHFFFAOYSA-N
InChI=1S/C20H12F4N4O3S/c21-14-7-10(2-3-12(14)16(29)30)28-18(32)27(17(31)19(28)4-1-5-19)11-6-13(20(22,23)24)15(8-25)26-9-11/h2-3,6-7,9H,1,4-5H2,(H,29,30)
| Molecular Formula | C20H12F4N4O3S |
| Molecular Weight | 464.393 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Thu Jul 06 19:39:53 UTC 2023
by
admin
on
Thu Jul 06 19:39:53 UTC 2023
|
| Record UNII |
Y58Z86OCE2
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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| Code System | Code | Type | Description | ||
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86683488
Created by
admin on Thu Jul 06 19:39:54 UTC 2023 , Edited by admin on Thu Jul 06 19:39:54 UTC 2023
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PRIMARY | |||
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Y58Z86OCE2
Created by
admin on Thu Jul 06 19:39:54 UTC 2023 , Edited by admin on Thu Jul 06 19:39:54 UTC 2023
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PRIMARY | |||
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1332391-04-4
Created by
admin on Thu Jul 06 19:39:54 UTC 2023 , Edited by admin on Thu Jul 06 19:39:54 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
TARGET -> INHIBITOR |
OFF-TARGET ACTIVITY: INHIBITING LIGAND BINDING TO THE AGBAA CHLORIDE ION CHANNEL
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| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE INACTIVE |
after oral administration of 240 mg of apalutamide in 0-1680 hours
URINE
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||
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PARENT -> METABOLITE |
after oral administration of 240 mg of apalutamide in 0-1680 hours
FECAL
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PARENT -> METABOLITE |
PLASMA
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