Halicin

NC1=NN=C(SC2=NC=C(S2)[N+]([O-])=O)S1

InChIKey=NQQBNZBOOHHVQP-UHFFFAOYSA-N

InChI=1S/C5H3N5O2S3/c6-3-8-9-5(14-3)15-4-7-1-2(13-4)10(11)12/h1H,(H2,6,8)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
c-Jun N-terminal kinase, JNK 7 Target ID: CHEMBL2096667 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19271755	Inhibitor 8297		0.7 µM [IC50]

PubMed

Title	Date	PubMed
Design, synthesis, and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-Jun N-terminal kinase.	2009 Apr 9	19271755

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:04:05 GMT 2023` Edited by `admin` on `Sat Dec 16 17:04:05 GMT 2023`
Record UNII	Y4KQC5P9B2
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

Halicin

Common Name

English

SU-3327

Code

English

5-[(5-Nitro-2-thiazolyl)thio]-1,3,4-thiadiazol-2-amine

Systematic Name

English

1,3,4-Thiadiazol-2-amine, 5-[(5-nitro-2-thiazolyl)thio]-

Systematic Name

English

SU3327

Code

English

Code System Code Type Description

EPA CompTox

DTXSID70474254