GLPG-0974

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C25H25ClN2O4S
Molecular Weight	484.995
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@@]1(CCN1C(=O)C2=CSC3=CC=CC=C23)C(=O)N(CCCC(O)=O)CC4=CC(Cl)=CC=C4

InChI

InChIKey=MPMKMQHJHDHPBE-RUZDIDTESA-N

InChI=1S/C25H25ClN2O4S/c1-25(11-13-28(25)23(31)20-16-33-21-9-3-2-8-19(20)21)24(32)27(12-5-10-22(29)30)15-17-6-4-7-18(26)14-17/h2-4,6-9,14,16H,5,10-13,15H2,1H3,(H,29,30)/t25-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C25H25ClN2O4S
Molecular Weight	484.995
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Free fatty acid receptor 2 1 Target ID: CHEMBL5493 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28526687	Antagonist 2778

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 13:37:57 UTC 2023` Edited by `admin` on `Sat Dec 16 13:37:57 UTC 2023`
Record UNII	X7REK61AIS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GLPG-0974

Code

English

4-((((2R)-1-(BENZO(B)THIEN-3-YLCARBONYL)-2-METHYL-2-AZETIDINYL)CARBONYL)((3-CHLOROPHENYL)METHYL)AMINO)BUTANOIC ACID

Systematic Name

English

BUTANOIC ACID, 4-((((2R)-1-(BENZO(B)THIEN-3-YLCARBONYL)-2-METHYL-2-AZETIDINYL)CARBONYL)((3-CHLOROPHENYL)METHYL)AMINO)-

Systematic Name

English

4-(((R)-1-(BENZO(B)THIOPHENE-3-CARBONYL)-2-METHYL-AZETIDINE-2-CARBONYL)-(3-CHLORO-BENZYL)-AMINO)-BUTYRIC ACID

Systematic Name

English

GLPG0974

Code

English

Code System Code Type Description

DRUG BANK

DB15406