TEPIRINDOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H19ClN2
Molecular Weight	274.788
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCN1CCC(=CC1)C2=CNC3=C2C=C(Cl)C=C3

InChI

InChIKey=ZRCUMOBNOPSLKM-UHFFFAOYSA-N

InChI=1S/C16H19ClN2/c1-2-7-19-8-5-12(6-9-19)15-11-18-16-4-3-13(17)10-14(15)16/h3-5,10-11,18H,2,6-9H2,1H3

HIDE SMILES / InChI

Molecular Formula	C16H19ClN2
Molecular Weight	274.788
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2342229 | Annual Reports in Medicinal Chemistry, V. 22, p. 6, retrieved from: https://books.google.ru/books?id=oJeTSJveeuAC&pg=PA6&lpg=PA6&dq=HR-592+TEPIRINDOLE&source=bl&ots=9bsWMHLDKh&sig=ACfU3U152dpzs8c_kfJ3eL-3VSIz13dd8w&hl=ru&sa=X&ved=2ahUKEwjL_IXp-qnjAhVCxMQBHdlCCgEQ6AEwA3oECAgQAQ#v=onepage&q=HR-592%20TEPIRINDOLE&f=false

Tepirindole (also known as HR-592), an indole derivative has a high affinity for DA, 5-HT and NE receptors but has little properties to cause catalepsy. Animal experiments have shown that this compound could alleviate the adverse effect of neuroleptics such as haloperidol. Information about the current development of tepirindole is not available.

Approval Year

PubMed

Title	Date	PubMed
Behavioral effects of HR-592, a new derivative of indole.	1990 Apr	2342229
Effects of HR-592, a new derivative of indole, on conditioned behavior.	1990 Feb	2330844

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:12:22 GMT 2023` Edited by `admin` on `Fri Dec 15 16:12:22 GMT 2023`
Record UNII	X235XX30GK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TEPIRINDOLE

Official Name

English

tepirindole [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66883