U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Details

Stereochemistry ACHIRAL
Molecular Formula C16H19ClN2
Molecular Weight 274.788
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TEPIRINDOLE

SMILES

CCCN1CCC(=CC1)C2=CNC3=C2C=C(Cl)C=C3

InChI

InChIKey=ZRCUMOBNOPSLKM-UHFFFAOYSA-N
InChI=1S/C16H19ClN2/c1-2-7-19-8-5-12(6-9-19)15-11-18-16-4-3-13(17)10-14(15)16/h3-5,10-11,18H,2,6-9H2,1H3

HIDE SMILES / InChI

Molecular Formula C16H19ClN2
Molecular Weight 274.788
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Tepirindole (also known as HR-592), an indole derivative has a high affinity for DA, 5-HT and NE receptors but has little properties to cause catalepsy. Animal experiments have shown that this compound could alleviate the adverse effect of neuroleptics such as haloperidol. Information about the current development of tepirindole is not available.

Approval Year

PubMed

Substance Class Chemical
Record UNII
X235XX30GK
Record Status Validated (UNII)
Record Version