Ciduvectamig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 11:08:15 GMT 2025` Edited by `admin` on `Wed Apr 02 11:08:15 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG4
Sequence Type	COMPLETE
Record UNII	VJH7ED7HR8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Ciduvectamig

Official Name

English

Ciduvectamig (immunoglobulin G4-kappa/lambda2, anti-[Homo sapiens TMEFF2 (transmembrane protein with EGF like and two follistatin like domains 2, cancer/testis antigen family 120 member 2, CT120.2, tomor?guline)] and anti-[Homo sapiens CD3E (CD3e, CD3 ep

Preferred Name

English

Immunoglobulin G4 [228-proline,234-alanine,235-alanine,405-leucine,409-lysine], anti-(human CD3 antigen ?-chain) (human monoclonal CD3B376 ?4-chain), disulfide with human monoclonal CD3B376 ?-chain, (226.fwdarw.224?),(229.fwdarw.227?)-bis(disulfide) with

Common Name

English

ciduvectamig [INN]

Common Name

English

Code System Code Type Description

FDA UNII

VJH7ED7HR8

Created by admin on Wed Apr 02 11:08:15 GMT 2025 , Edited by admin on Wed Apr 02 11:08:15 GMT 2025

PRIMARY

CAS

2412587-62-1

Created by admin on Wed Apr 02 11:08:15 GMT 2025 , Edited by admin on Wed Apr 02 11:08:15 GMT 2025

PRIMARY

INN

12199

Created by admin on Wed Apr 02 11:08:15 GMT 2025 , Edited by admin on Wed Apr 02 11:08:15 GMT 2025

PRIMARY

NCI_THESAURUS

C203044

Created by admin on Wed Apr 02 11:08:15 GMT 2025 , Edited by admin on Wed Apr 02 11:08:15 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_99
2_134	4_215
2_147	2_203
2_261	2_321
1_132	3_214
2_367	2_425
3_23	3_88
3_134	3_194
4_22	4_90
4_138	4_197
1_145	1_201
1_224	2_226
1_227	2_229
1_259	1_319
1_365	1_423

Glycosylation Link Type	Site
N	1_295
N	2_297

Related Record Type Details


					VJH7ED7HR8

Ciduvectamig

ACTIVE MOIETY

Comments:

Pre-clinical

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION		N-TERMINUS		Amount:	PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL		C-TERMINUS		Amount:	LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL