Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C17H17NO2 |
| Molecular Weight | 267.323 |
| Optical Activity | ( - ) |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
c1ccc2c(c1)CN[C@@]3([H])CCc4cc(c(cc4[C@]23[H])O)O
InChI
InChIKey=BGOQGUHWXBGXJW-YOEHRIQHSA-N
InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m0/s1
| Molecular Formula | C17H17NO2 |
| Molecular Weight | 267.323 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist. Dihydrexidine was shown to stimulate cyclic AMP synthesis just as well or better than dopamine. It was the first dopamine D1 receptor agonist that had potent antiparkinsonian activity in a primate model of Parkinson's disease. Dihydrexidine produces hypothermia. Dihydrexidine has been shown to alleviate cognitive deficits or enhance cognitive performance in a number of animal models of cognition. It is under investigation for the improving the cognitive and working memory deficits in schizophrenia and schizotypal disorder.
CNS Activity
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Jun 26 15:45:45 UTC 2021
by
admin
on
Sat Jun 26 15:45:45 UTC 2021
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| Record UNII |
U4MPC92UC2
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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757161-85-6
Created by
admin on Sat Jun 26 15:45:45 UTC 2021 , Edited by admin on Sat Jun 26 15:45:45 UTC 2021
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U4MPC92UC2
Created by
admin on Sat Jun 26 15:45:45 UTC 2021 , Edited by admin on Sat Jun 26 15:45:45 UTC 2021
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5311070
Created by
admin on Sat Jun 26 15:45:45 UTC 2021 , Edited by admin on Sat Jun 26 15:45:45 UTC 2021
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TARGET -> AGONIST | |||
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INNOVATOR->PARENT | |||
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ENANTIOMER -> ENANTIOMER | |||
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RACEMATE -> ENANTIOMER |
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ACTIVE MOIETY |
