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Details

Stereochemistry ACHIRAL
Molecular Formula C19H21ClN2OS
Molecular Weight 360.901
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHLORACYZINE

SMILES

CCN(CC)CCC(=O)N1C2=CC(Cl)=CC=C2SC3=C1C=CC=C3

InChI

InChIKey=ZZKWNLZUYAGVOT-UHFFFAOYSA-N
InChI=1S/C19H21ClN2OS/c1-3-21(4-2)12-11-19(23)22-15-7-5-6-8-17(15)24-18-10-9-14(20)13-16(18)22/h5-10,13H,3-4,11-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C19H21ClN2OS
Molecular Weight 360.901
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Chloracyzine is phenothiazine derivative with vasodilatory activity. Chloracyzine produced a decrease in myocardial oxygen consumption accompanied by a reduction in coronary blood flow preceded by transient coronary dilatation. Chloracyzine produced an insignificant increase in arterial pressure; heart rate increased slightly in the open-chest experiments but not in the isolated heart. It is suggested that reduced oxygen uptake after chloracyzine is realized through improved efficiency in the use of oxygen.

Originator

Approval Year

PubMed

Patents

Substance Class Chemical
Record UNII
TZ913SWN6M
Record Status Validated (UNII)
Record Version