Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C21H28N2O2.ClH |
| Molecular Weight | 376.92 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.OCCOCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChIKey=DDKYRGRSMTYEPD-UHFFFAOYSA-N
InChI=1S/C21H28N2O2.ClH/c24-16-18-25-17-15-22-11-13-23(14-12-22)21(19-7-3-1-4-8-19)20-9-5-2-6-10-20;/h1-10,21,24H,11-18H2;1H
| Molecular Formula | C21H28N2O2 |
| Molecular Weight | 340.4592 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: CHEMBL231 Sources: https://www.medchemexpress.com/decloxizine.html |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Primary | Unknown Approved UseUnknown |
|||
| Primary | Unknown Approved UseUnknown |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effect of decloxizine on histamine aerosol induced bronchoconstriction in the conscious guinea-pig. | 1969-11 |
|
| Bronchodilator action of drug combinations in asthmatic patients: decloxizine, orciprenaline, and ephedrine. | 1969-06 |
|
| [Preliminary study of effects of decloxizine on air passage resistance in chronic bronchitis patients]. | 1968-07-01 |
|
| [Protective effect of decloxizine in relation to bronchospasm due to histamine]. | 1968-07-01 |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4395228
Curator's Comment: Intravenous route is possible
https://www.ncbi.nlm.nih.gov/pubmed/4904306
Three daily 50 mg doses of decloxizine proved sufficient to prevent asthma attacks and shortness of breath in the patients examined
Route of Administration:
Oral
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:02:35 GMT 2025
by
admin
on
Mon Mar 31 23:02:35 GMT 2025
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| Record UNII |
TWC294RL1T
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| Record Status |
Validated (UNII)
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| Record Version |
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1263283-80-2
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admin on Mon Mar 31 23:02:35 GMT 2025 , Edited by admin on Mon Mar 31 23:02:35 GMT 2025
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TWC294RL1T
Created by
admin on Mon Mar 31 23:02:35 GMT 2025 , Edited by admin on Mon Mar 31 23:02:35 GMT 2025
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