Details
Stereochemistry | ACHIRAL |
Molecular Formula | C21H28N2O2 |
Molecular Weight | 340.4592 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OCCOCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChIKey=OXBBIHZWNDPBMQ-UHFFFAOYSA-N
InChI=1S/C21H28N2O2/c24-16-18-25-17-15-22-11-13-23(14-12-22)21(19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-10,21,24H,11-18H2
Molecular Formula | C21H28N2O2 |
Molecular Weight | 340.4592 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL231 Sources: https://www.medchemexpress.com/decloxizine.html |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Primary | Unknown Approved UseUnknown |
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Primary | Unknown Approved UseUnknown |
PubMed
Title | Date | PubMed |
---|---|---|
[Preliminary study of effects of decloxizine on air passage resistance in chronic bronchitis patients]. | 1968 Jul-Oct |
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Bronchodilator action of drug combinations in asthmatic patients: decloxizine, orciprenaline, and ephedrine. | 1969 Jun |
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Effect of decloxizine on histamine aerosol induced bronchoconstriction in the conscious guinea-pig. | 1969 Nov |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4395228
Curator's Comment: Intravenous route is possible
https://www.ncbi.nlm.nih.gov/pubmed/4904306
Three daily 50 mg doses of decloxizine proved sufficient to prevent asthma attacks and shortness of breath in the patients examined
Route of Administration:
Oral
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:33:17 GMT 2023
by
admin
on
Fri Dec 15 16:33:17 GMT 2023
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Record UNII |
919C49XAYD
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C29578
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DTXSID40190777
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CHEMBL2106665
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2476
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SUB06936MIG
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100000083493
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C76673
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3733-63-9
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919C49XAYD
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289116
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71135
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Related Record | Type | Details | ||
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
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Related Record | Type | Details | ||
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ACTIVE MOIETY |