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Details

Stereochemistry ABSOLUTE
Molecular Formula C26H35N3O5
Molecular Weight 469.5732
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIMETHYLAMINOETHYL RESERPILINATE

SMILES

COC1=C(OC)C=C2C(NC3=C2CCN4C[C@H]5[C@H](C)OC=C([C@H]5C[C@H]34)C(=O)OCCN(C)C)=C1

InChI

InChIKey=GKMCARMHFZCZDR-MNNBHYOVSA-N
InChI=1S/C26H35N3O5/c1-15-19-13-29-7-6-16-18-11-23(31-4)24(32-5)12-21(18)27-25(16)22(29)10-17(19)20(14-34-15)26(30)33-9-8-28(2)3/h11-12,14-15,17,19,22,27H,6-10,13H2,1-5H3/t15-,17-,19-,22+/m0/s1

HIDE SMILES / InChI
Molecular Formula C26H35N3O5
Molecular Weight 469.5732
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Dimethylaminoethyl reserpilinate is reserpilinate derivative with hypotensive activity. Given subcutaneously to rats in doses 200 mg/kg dimethylaminoethane reserpilinate increased very slightly the gastric motility but showed no ulcerogenic effect.

Originator

La Barre, J.|Gillo, L.
2

Approval Year

Unknown
149,124

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Patents

WO2012091730
2

Sample Use Guides

In Vivo Use Guide
200 mg/kg
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
T82CYV41KX
Record Status Validated (UNII)
Record Version
NIH
NCATS
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