DIMETHYLAMINOETHYL RESERPILINATE DIHYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H35N3O5.2ClH
Molecular Weight	542.495
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DIMETHYLAMINOETHYL RESERPILINATE DIHYDROCHLORIDE

Structure Search

SMILES

Cl.Cl.[H][C@]12C[C@]3([H])C(=CO[C@@H](C)[C@]3([H])CN1CCC4=C2NC5=C4C=C(OC)C(OC)=C5)C(=O)OCCN(C)C

InChI

InChIKey=RDKIYVYHCBJDMF-DGCKWTARSA-N

InChI=1S/C26H35N3O5.2ClH/c1-15-19-13-29-7-6-16-18-11-23(31-4)24(32-5)12-21(18)27-25(16)22(29)10-17(19)20(14-34-15)26(30)33-9-8-28(2)3;;/h11-12,14-15,17,19,22,27H,6-10,13H2,1-5H3;2*1H/t15-,17-,19-,22+;;/m0../s1

HIDE SMILES / InChI

Molecular Formula	C26H35N3O5
Molecular Weight	469.5732
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14282121
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/5977060 | https://www.ncbi.nlm.nih.gov/pubmed/13959902

Dimethylaminoethyl reserpilinate is reserpilinate derivative with hypotensive activity. Given subcutaneously to rats in doses 200 mg/kg dimethylaminoethane reserpilinate increased very slightly the gastric motility but showed no ulcerogenic effect.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
[Effects of dimethylaminoethyl reserpilinate on the stomach in rats].	1966 Oct	5977060

Patents

Sample Use Guides

In Vivo Use Guide

200 mg/kg

Route of Administration: Other

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:04:50 GMT 2023` Edited by `admin` on `Fri Dec 15 16:04:50 GMT 2023`
Record UNII	D1301HM9JD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIMETHYLAMINOETHYL RESERPILINATE DIHYDROCHLORIDE

Common Name

English

RESERPILIC ACID DIMETHYLAMINOETHYL ESTER DIHYDROCHLORIDE [MI]

Common Name

English

RESERPILIC ACID DIMETHYLAMINOETHYL ESTER DIHYDROCHLORIDE

Common Name

English

PARATENSIOL

Brand Name

English

RESPORISAN

Brand Name

English

DIMETHYLAMINOETHYLRESERPILINATE HCL

Common Name

English

DIMETHYLAMINOETHYL RESERPILINATE DIHYDROCHLORIDE [JAN]

Common Name

English

Dimethylaminoethylreserpilinate hcl [WHO-DD]

Common Name

English

DIMETHYLAMINOETHYL 16,17-DIDEHYDRO-10,11-DIMETHOXY-19.ALPHA.-METHYL-3.BETA.,20.ALPHA.-OXAYOHIMBAN-16-CARBOXYLATE DIHYDROCHLORIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C270