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Details

Stereochemistry RACEMIC
Molecular Formula C11H16ClNO.ClH.H2O
Molecular Weight 268.18
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLORPRENALINE HYDROCHLORIDE

SMILES

O.Cl.CC(C)NCC(O)C1=C(Cl)C=CC=C1

InChI

InChIKey=DBPRUZCKPFOVDV-UHFFFAOYSA-N
InChI=1S/C11H16ClNO.ClH.H2O/c1-8(2)13-7-11(14)9-5-3-4-6-10(9)12;;/h3-6,8,11,13-14H,7H2,1-2H3;1H;1H2

HIDE SMILES / InChI
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C11H16ClNO
Molecular Weight 213.704
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/25285506 | https://www.ncbi.nlm.nih.gov/pubmed/13376372

Clorprenaline is a β2-adrenergic receptor agonist. As a bronchodilator it has been used for the treatment of bronchial asthma, bronchitis and other respiratory diseases. It is a potential new lean meat-boosting feed additive because it can promote animal muscular mass growth and decrease fat accumulation.

Originator

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Agonist
2678
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8429
Unknown

Approved Use

Clorprenaline has been commonly used for the treatment of bronchial asthma, bronchitis and other respiratory diseases in clinical.
PubMed

PubMed

TitleDatePubMed
Determination of beta2-agonists by ion chromatography with direct conductivity detection.
2005 Jun 1
[Simultaneous determination of nine beta-agonist residues in animal derived foods by ultra performance liquid chromatography-tandem mass spectrometry].
2008 Nov
N-[2-(2-Chloro-phen-yl)-2-hydroxy-ethyl]propan-2-aminium hemioxalate.
2009 Jun 24
1-(2-Chloro-phen-yl)-2-(isopropyl-amino)ethanol.
2009 Jun 6
[Determination of fifteen beta-agonists in animal urine by high performance liquid chromatography-tandem mass spectrometry].
2010 Aug
N-[2-(2-Chloro-phen-yl)-2-hydroxy-ethyl]propan-2-aminium nitrate.
2010 Jan 16
Patents

Patents

JPS617238A
3
JPS62106013A
3

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:59:01 GMT 2023
Edited
by admin
on Fri Dec 15 15:59:01 GMT 2023
Record UNII
T6CRE6WE0W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CLORPRENALINE HYDROCHLORIDE
MART.   USAN   WHO-DD  
USAN  
Official Name English
CLORPRENALINE HYDROCHLORIDE MONOHYDRATE
MART.   MI  
Common Name English
CONSELT
Brand Name English
CLOPINERIN
Brand Name English
CLORPRENALINE HYDROCHLORIDE [MART.]
Common Name English
CLORPRENALINE HYDROCHLORIDE MONOHYDRATE [MART.]
Common Name English
O-Chloro-α[(isopropylamino)methyl]benzyl alcohol hydrochloride monohydrate
Common Name English
RESTANOLON
Brand Name English
FUSCA
Brand Name English
BRONCON
Brand Name English
BENZENEMETHANOL, 2-CHLORO-.ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)-, HYDROCHLORIDE, MONOHYDRATE
Systematic Name English
CLORPRENALINE HYDROCHLORIDE MONOHYDRATE [MI]
Common Name English
20025
Code English
CLORPRENALINE HCL
Common Name English
PENTADOLL
Brand Name English
KALUTEIN
Brand Name English
Clorprenaline hydrochloride [WHO-DD]
Common Name English
CLORPRENALINE HYDROCHLORIDE [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C319
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
NCI_THESAURUS C48149
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
Code System Code Type Description
FDA UNII
T6CRE6WE0W
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
PRIMARY
ChEMBL
CHEMBL1902627
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
PRIMARY
SMS_ID
100000087959
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
PRIMARY
MERCK INDEX
m1086
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
PRIMARY Merck Index
NCI_THESAURUS
C65343
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
PRIMARY
EPA CompTox
DTXSID80971284
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
PRIMARY
MESH
C004350
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
PRIMARY
CAS
5588-22-7
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
PRIMARY
PUBCHEM
21784
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
PRIMARY
EVMPD
SUB01373MIG
Created by admin on Fri Dec 15 15:59:01 GMT 2023 , Edited by admin on Fri Dec 15 15:59:01 GMT 2023
PRIMARY
Related Record Type Details
Structure of CLORPRENALINE HYDROCHLORIDE ANHYDROUS
ANHYDROUS->SOLVATE
Structure of CLORPRENALINE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of CLORPRENALINE
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