CLORPRENALINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H16ClNO
Molecular Weight	213.704
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)NCC(O)C1=C(Cl)C=CC=C1

InChI

InChIKey=SSMSBSWKLKKXGG-UHFFFAOYSA-N

InChI=1S/C11H16ClNO/c1-8(2)13-7-11(14)9-5-3-4-6-10(9)12/h3-6,8,11,13-14H,7H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C11H16ClNO
Molecular Weight	213.704
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: http://www.chemicalbook.com/ChemicalProductProperty_EN_CB2291187.htm
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/25285506 | https://www.ncbi.nlm.nih.gov/pubmed/13376372

Clorprenaline is a β2-adrenergic receptor agonist. As a bronchodilator it has been used for the treatment of bronchial asthma, bronchitis and other respiratory diseases. It is a potential new lean meat-boosting feed additive because it can promote animal muscular mass growth and decrease fat accumulation.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Beta-2 adrenergic receptor 203 Target ID: CHEMBL210 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26002106 \| https://www.ncbi.nlm.nih.gov/pubmed/27859454	Agonist 2678

Conditions

Condition	Modality	Targets	Highest Phase	Product
Asthma 241 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14400681 https://www.ncbi.nlm.nih.gov/pubmed/13868694	Primary		Approved 8429	Unknown Approved Use Clorprenaline has been commonly used for the treatment of bronchial asthma, bronchitis and other respiratory diseases in clinical.

PubMed

Title	Date	PubMed
Determination of beta2-agonists by ion chromatography with direct conductivity detection.	2005 Jun 1	15907636
[Simultaneous determination of nine beta-agonist residues in animal derived foods by ultra performance liquid chromatography-tandem mass spectrometry].	2008 Nov	19253549
N-[2-(2-Chloro-phen-yl)-2-hydroxy-ethyl]propan-2-aminium chloride.	2009 Aug 19	21577591
N-[2-(2-Chloro-phen-yl)-2-hydroxy-ethyl]propan-2-aminium hemioxalate.	2009 Jun 24	21582930
1-(2-Chloro-phen-yl)-2-(isopropyl-amino)ethanol.	2009 Jun 6	21582800
[2-(2-Chloro-phen-yl)-2-hy-droxy-eth-yl](isoprop-yl)ammonium 4-hy-droxy-benzoate.	2010 Dec 18	21522694
N-[2-(2-Chloro-phen-yl)-2-hydroxy-ethyl]propan-2-aminium nitrate.	2010 Jan 16	21579812

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Other

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:29:27 UTC 2023` Edited by `admin` on `Fri Dec 15 15:29:27 UTC 2023`
Record UNII	3W4327W76O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLORPRENALINE

Official Name

English

clorprenaline [INN]

Common Name

English

CLORPRENALINE [MI]

Common Name

English

ORTHO-CHLORO-.ALPHA.((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL

Systematic Name

English

BENZENEMETHANOL, 2-CHLORO-.ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)

Common Name

English

Clorprenaline [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C48149