CLORPRENALINE HYDROCHLORIDE ANHYDROUS

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H16ClNO.ClH
Molecular Weight	250.165
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CLORPRENALINE HYDROCHLORIDE ANHYDROUS

Structure Search

SMILES

Cl.CC(C)NCC(O)C1=CC=CC=C1Cl

InChI

InChIKey=CPCPUCRSKRHVAH-UHFFFAOYSA-N

InChI=1S/C11H16ClNO.ClH/c1-8(2)13-7-11(14)9-5-3-4-6-10(9)12;/h3-6,8,11,13-14H,7H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C11H16ClNO
Molecular Weight	213.704
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: http://www.chemicalbook.com/ChemicalProductProperty_EN_CB2291187.htm
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/25285506 | https://www.ncbi.nlm.nih.gov/pubmed/13376372

Clorprenaline is a β2-adrenergic receptor agonist. As a bronchodilator it has been used for the treatment of bronchial asthma, bronchitis and other respiratory diseases. It is a potential new lean meat-boosting feed additive because it can promote animal muscular mass growth and decrease fat accumulation.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Beta-2 adrenergic receptor 203 Target ID: CHEMBL210 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26002106 \| https://www.ncbi.nlm.nih.gov/pubmed/27859454	Agonist 2678

Conditions

Condition	Modality	Targets	Highest Phase	Product
Asthma 241 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14400681 https://www.ncbi.nlm.nih.gov/pubmed/13868694	Primary		Approved 8429	Unknown Approved Use Clorprenaline has been commonly used for the treatment of bronchial asthma, bronchitis and other respiratory diseases in clinical.

PubMed

Title	Date	PubMed
Determination of beta2-agonists by ion chromatography with direct conductivity detection.	2005 Jun 1	15907636
Simultaneous separation of eight beta-adrenergic drugs using titanium dioxide nanoparticles as additive in capillary electrophoresis.	2008 Jun	18435493
[Simultaneous determination of nine beta-agonist residues in animal derived foods by ultra performance liquid chromatography-tandem mass spectrometry].	2008 Nov	19253549
N-[2-(2-Chloro-phen-yl)-2-hydroxy-ethyl]propan-2-aminium chloride.	2009 Aug 19	21577591
N-[2-(2-Chloro-phen-yl)-2-hydroxy-ethyl]propan-2-aminium hemioxalate.	2009 Jun 24	21582930
1-(2-Chloro-phen-yl)-2-(isopropyl-amino)ethanol.	2009 Jun 6	21582800
[Determination of fifteen beta-agonists in animal urine by high performance liquid chromatography-tandem mass spectrometry].	2010 Aug	21261043
[2-(2-Chloro-phen-yl)-2-hy-droxy-eth-yl](isoprop-yl)ammonium 4-hy-droxy-benzoate.	2010 Dec 18	21522694
N-[2-(2-Chloro-phen-yl)-2-hydroxy-ethyl]propan-2-aminium nitrate.	2010 Jan 16	21579812

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Other

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:14:11 GMT 2023` Edited by `admin` on `Fri Dec 15 17:14:11 GMT 2023`
Record UNII	H34A8V28IT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLORPRENALINE HYDROCHLORIDE ANHYDROUS

Common Name

English

BENZENEMETHANOL, 2-CHLORO-.ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)-, HYDROCHLORIDE

Systematic Name

English

NSC-334693

Code

English

ANHYDROUS CLORPRENALINE HYDROCHLORIDE

Common Name

English

CLORPRENALINE HYDROCHLORIDE [JAN]

Common Name

English

O-CHLORO-.ALPHA.((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL HYDROCHLORIDE

Common Name

English

ANHYDROUS CLORPRENALINE HYDROCHLORIDE [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C48149