QUERCETAGETIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H10O8
Molecular Weight	318.2351
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=C(C=C1O)C2=C(O)C(=O)C3=C(O2)C=C(O)C(O)=C3O

InChI

InChIKey=ZVOLCUVKHLEPEV-UHFFFAOYSA-N

InChI=1S/C15H10O8/c16-6-2-1-5(3-7(6)17)15-14(22)13(21)10-9(23-15)4-8(18)11(19)12(10)20/h1-4,16-20,22H

HIDE SMILES / InChI

Molecular Formula	C15H10O8
Molecular Weight	318.2351
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes.	2013-01	23349632
The flavonoids luteolin and quercetagetin inhibit lipoteichoic acid actions on H9c2 cardiomyocytes.	2010-09	20685402
Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements.	2010-08-16	20808948
Transcriptional regulation of Pim-1 kinase in vascular smooth muscle cells and its role for proliferation.	2010-03	19711112
Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs.	2010-01	22228937
Antioxidant effects of Glechoma hederacea as a food additive.	2010-01	20184023
[Bioactivity guided isolation of alpha-glucosidase inhibitor from whole herbs of Crossostephium chinense].	2009-09	19943487
Free radical scavengers and antioxidants from Tagetes mendocina.	2008-11-13	18998399
Structure-activity relationships of flavonoids as potential inhibitors of glycogen phosphorylase.	2008-06-25	18494482
Biochemical and structural analysis of substrate promiscuity in plant Mg2+-dependent O-methyltransferases.	2008-04-18	18342334
The impact of the human DNA topoisomerase II C-terminal domain on activity.	2008-03-12	18335031
[Effects of quercetin on human laryngeal cancer Hep-2 cells].	2008-02	18476622
Effects of various methoxyflavones on vincristine uptake and multidrug resistance to vincristine in P-gp-overexpressing K562/ADM cells.	2007-10	17492365
The effect of flavonoids on transduction mechanisms in lipopolysaccharide-treated human gingival fibroblasts.	2007-09	17630199
Structure-activity relationship of flavonoids for inhibition of epidermal growth factor-induced transformation of JB6 Cl 41 cells.	2007-06	17219438
Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.	2007-01	17218638
Antifungal and antibacterial activities of Mexican tarragon (Tagetes lucida).	2006-05-17	19127719
Pro-oxidative effect of beta-carotene and the interaction with flavonoids on UVA-induced DNA strand breaks in mouse fibroblast C3H10T1/2 cells.	2005-12	16098732
Molecular targets of dietary polyphenols with anti-inflammatory properties.	2005-10-31	16259055
Acylated quercetagetin glycosides with antioxidant activity from Tagetes maxima.	2005-10	16168446
Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels.	2004-10	15378228
Kinetic study of flavonoid reactions with stable radicals.	2004-05-19	15137819
G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.).	2004-05-10	15105046
Variations in lipophilic and vacuolar flavonoids among European Pulicaria species.	2003-09	12946426
Sesquiterpene lactones from Anthemis altissima and their anti-Helicobacter pylori activity.	2003-05	12762812
Identification of lipophilic flavones and flavonols by comparative HPLC, TLC and UV spectral analysis.	2003-04-16	12693635
Human immunodeficiency virus type 1 cDNA integration: new aromatic hydroxylated inhibitors and studies of the inhibition mechanism.	1998-09	9736543
Discovery and analysis of inhibitors of the human immunodeficiency integrase.	1997-05	9332828
Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds.	1997-01	8985421
Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules.	1996-09-03	8790401
Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds.	1994-08-03	7520698
Effects of flavonoids on Naja naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice.	1994	8190018
Flavones are inhibitors of HIV-1 proteinase.	1992-10-30	1445308
Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases.	1990-07-05	1695572
Induction of Mx-related protein in cat peripheral blood mononuclear cells after administration of recombinant human interferon hybrid.	1990-02	2160795

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:40:26 GMT 2025` Edited by `admin` on `Mon Mar 31 20:40:26 GMT 2025`
Record UNII	SV68G507VO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-115916

Preferred Name

English

QUERCETAGETIN

Official Name

English

QUERCETAGETIN [MI]

Common Name

English

2-(3,4-DIHYDROXYPHENYL)-3,5,6,7-TETRAHYDROXY-4H-1-BENZOPYRAN-4-ONE

Systematic Name

English

4H-1-BENZOPYRAN-4-ONE, 2-(3,4-DIHYDROXYPHENYL)-3,5,6,7-TETRAHYDROXY-

Systematic Name

English

6-HYDROXYQUERCETIN

Common Name

English

3,3',4',5,6,7-HEXAHYDROXYFLAVONE

Systematic Name

English

Code System Code Type Description

NSC

115916