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Details

Stereochemistry ACHIRAL
Molecular Formula C15H10O8.2H2O
Molecular Weight 354.2657
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of QUERCETAGETIN DIHYDRATE

SMILES

O.O.OC1=CC2=C(C(=O)C(O)=C(O2)C3=CC(O)=C(O)C=C3)C(O)=C1O

InChI

InChIKey=PGHJCMBXWXXCBQ-UHFFFAOYSA-N
InChI=1S/C15H10O8.2H2O/c16-6-2-1-5(3-7(6)17)15-14(22)13(21)10-9(23-15)4-8(18)11(19)12(10)20;;/h1-4,16-20,22H;2*1H2

HIDE SMILES / InChI

Molecular Formula C15H10O8
Molecular Weight 318.2351
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes.
2013-01
The flavonoids luteolin and quercetagetin inhibit lipoteichoic acid actions on H9c2 cardiomyocytes.
2010-09
Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements.
2010-08-16
Transcriptional regulation of Pim-1 kinase in vascular smooth muscle cells and its role for proliferation.
2010-03
Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs.
2010-01
Antioxidant effects of Glechoma hederacea as a food additive.
2010-01
[Bioactivity guided isolation of alpha-glucosidase inhibitor from whole herbs of Crossostephium chinense].
2009-09
Free radical scavengers and antioxidants from Tagetes mendocina.
2008-11-13
Structure-activity relationships of flavonoids as potential inhibitors of glycogen phosphorylase.
2008-06-25
Biochemical and structural analysis of substrate promiscuity in plant Mg2+-dependent O-methyltransferases.
2008-04-18
The impact of the human DNA topoisomerase II C-terminal domain on activity.
2008-03-12
[Effects of quercetin on human laryngeal cancer Hep-2 cells].
2008-02
Effects of various methoxyflavones on vincristine uptake and multidrug resistance to vincristine in P-gp-overexpressing K562/ADM cells.
2007-10
The effect of flavonoids on transduction mechanisms in lipopolysaccharide-treated human gingival fibroblasts.
2007-09
Structure-activity relationship of flavonoids for inhibition of epidermal growth factor-induced transformation of JB6 Cl 41 cells.
2007-06
Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.
2007-01
Antifungal and antibacterial activities of Mexican tarragon (Tagetes lucida).
2006-05-17
Pro-oxidative effect of beta-carotene and the interaction with flavonoids on UVA-induced DNA strand breaks in mouse fibroblast C3H10T1/2 cells.
2005-12
Molecular targets of dietary polyphenols with anti-inflammatory properties.
2005-10-31
Acylated quercetagetin glycosides with antioxidant activity from Tagetes maxima.
2005-10
Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels.
2004-10
Kinetic study of flavonoid reactions with stable radicals.
2004-05-19
G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.).
2004-05-10
Variations in lipophilic and vacuolar flavonoids among European Pulicaria species.
2003-09
Sesquiterpene lactones from Anthemis altissima and their anti-Helicobacter pylori activity.
2003-05
Identification of lipophilic flavones and flavonols by comparative HPLC, TLC and UV spectral analysis.
2003-04-16
Human immunodeficiency virus type 1 cDNA integration: new aromatic hydroxylated inhibitors and studies of the inhibition mechanism.
1998-09
Discovery and analysis of inhibitors of the human immunodeficiency integrase.
1997-05
Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds.
1997-01
Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules.
1996-09-03
Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds.
1994-08-03
Effects of flavonoids on Naja naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice.
1994
Flavones are inhibitors of HIV-1 proteinase.
1992-10-30
Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases.
1990-07-05
Induction of Mx-related protein in cat peripheral blood mononuclear cells after administration of recombinant human interferon hybrid.
1990-02
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:26:45 GMT 2025
Edited
by admin
on Mon Mar 31 21:26:45 GMT 2025
Record UNII
JTG0T7Z6SP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
QUERCETAGETIN DIHYDRATE
MI  
Common Name English
QUERCETAGETIN DIHYDRATE [MI]
Preferred Name English
2-(3,4-DIHYDROXYPHENYL)-3,5,6,7-TETRAHYDROXY-4H-1-BENZOPYRAN-4-ONE DIHYDRATE
Systematic Name English
Code System Code Type Description
MERCK INDEX
m9419
Created by admin on Mon Mar 31 21:26:45 GMT 2025 , Edited by admin on Mon Mar 31 21:26:45 GMT 2025
PRIMARY Merck Index
FDA UNII
JTG0T7Z6SP
Created by admin on Mon Mar 31 21:26:45 GMT 2025 , Edited by admin on Mon Mar 31 21:26:45 GMT 2025
PRIMARY
PUBCHEM
76969819
Created by admin on Mon Mar 31 21:26:45 GMT 2025 , Edited by admin on Mon Mar 31 21:26:45 GMT 2025
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE
Related Record Type Details
ACTIVE MOIETY