Lixudebart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 18:49:48 GMT 2023` Edited by `admin` on `Sat Dec 16 18:49:48 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	STN3UZ6YBJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Lixudebart

Official Name

English

ALE.F02

Code

English

Gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV3-21*01 (94.9%) -(IGHD) -IGHJ1*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, CH2 IGHG1v39 CH2 F1.3, E1.2, S116 (CH1 R120

Common Name

English

lixudebart [INN]

Common Name

English

Immunoglobulin G1 [236-phenylalanine,237-glutamic acid,333-serine,de-449-lysine], anti-(human claudin-1) (human-Rattus norvegicus monoclonal ALE.F02 γ1-chain), disulfide with human-Rattus norvegicus monoclonal ALE.F02 κ-chain, dimer

Common Name

English

Code System Code Type Description

CAS

2749515-10-2

Created by admin on Sat Dec 16 18:49:48 GMT 2023 , Edited by admin on Sat Dec 16 18:49:48 GMT 2023

PRIMARY

INN

12552

Created by admin on Sat Dec 16 18:49:48 GMT 2023 , Edited by admin on Sat Dec 16 18:49:48 GMT 2023

PRIMARY

FDA UNII

STN3UZ6YBJ

Created by admin on Sat Dec 16 18:49:48 GMT 2023 , Edited by admin on Sat Dec 16 18:49:48 GMT 2023

PRIMARY

NCI_THESAURUS

C199065

Created by admin on Sat Dec 16 18:49:48 GMT 2023 , Edited by admin on Sat Dec 16 18:49:48 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_146	2_202
2_222	4_214
2_263	2_323
1_146	1_202
2_369	2_427
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_222	3_214
1_228	2_228
1_231	2_231
1_263	1_323
1_369	1_427

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					STN3UZ6YBJ

Lixudebart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL