OXELADIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H33NO3
Molecular Weight	335.4809
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CC)CCOCCOC(=O)C(CC)(CC)C1=CC=CC=C1

InChI

InChIKey=IQADUMSPOQKAAO-UHFFFAOYSA-N

InChI=1S/C20H33NO3/c1-5-20(6-2,18-12-10-9-11-13-18)19(22)24-17-16-23-15-14-21(7-3)8-4/h9-13H,5-8,14-17H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C20H33NO3
Molecular Weight	335.4809
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.drugbank.ca/drugs/DB04822
Curator's Comment: Description was created based on several sources, including http://www.fda.gov.ph/consumers-corner/registered-drugs-2/337707-DR-X1387

Oxeladin citrate is a cough suppressant, is a highly potent and effective drug used to treat all types of cough of various etiologies. Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity. Oxeladine is a component of antitussive drug, Altussan, approved in Philippines.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Cough 106 Sources: http://www.mims.com/philippines/drug/info/altussan	Palliative		Approved 8429	Altussan Approved Use For the relief of all types of cough w/ acute and chronic inflammation due to upper and lower respiratory tract infections

PubMed

Title	Date	PubMed
High performance liquid chromatographic determination of oxeladin citrate and oxybutynin hydrochloride and their degradation products.	2005 Aug	16023117

Patents

Sample Use Guides

In Vivo Use Guide

Cap Adult 1 cap. Syr Adult 1 tbsp (15 mL). Childn 1 tsp (5 mL). Infant ¼-½ tsp (1.25-2.5 mL). All doses to be taken 3 hrly.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:12:58 GMT 2023` Edited by `admin` on `Fri Dec 15 15:12:58 GMT 2023`
Record UNII	SNC1080T5Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OXELADIN

Official Name

English

oxeladin [INN]

Common Name

English

Oxeladin [WHO-DD]

Common Name

English

OXELADIN [MI]

Common Name

English

2-(2-DIETHYLAMINOETHOXY)-ETHYL 2-ETHYL-2-PHENYLBUTYRATE

Systematic Name

English

Classification Tree Code System Code

WHO-VATC

QR05DB09