OXELADIN CITRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H33NO3.C6H8O7
Molecular Weight	527.6044
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)CCOCCOC(=O)C(CC)(CC)C1=CC=CC=C1

InChI

InChIKey=KVKJFNUGVOFNGU-UHFFFAOYSA-N

InChI=1S/C20H33NO3.C6H8O7/c1-5-20(6-2,18-12-10-9-11-13-18)19(22)24-17-16-23-15-14-21(7-3)8-4;7-3(8)1-6(13,5(11)12)2-4(9)10/h9-13H,5-8,14-17H2,1-4H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

HIDE SMILES / InChI

Molecular Formula	C20H33NO3
Molecular Weight	335.4809
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C6H8O7
Molecular Weight	192.1235
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.drugbank.ca/drugs/DB04822
Curator's Comment: Description was created based on several sources, including http://www.fda.gov.ph/consumers-corner/registered-drugs-2/337707-DR-X1387

Oxeladin citrate is a cough suppressant, is a highly potent and effective drug used to treat all types of cough of various etiologies. Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity. Oxeladine is a component of antitussive drug, Altussan, approved in Philippines.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Cough 106 Sources: http://www.mims.com/philippines/drug/info/altussan	Palliative		Approved 8429	Altussan Approved Use For the relief of all types of cough w/ acute and chronic inflammation due to upper and lower respiratory tract infections

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Cap Adult 1 cap. Syr Adult 1 tbsp (15 mL). Childn 1 tsp (5 mL). Infant ¼-½ tsp (1.25-2.5 mL). All doses to be taken 3 hrly.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:46:31 GMT 2023` Edited by `admin` on `Fri Dec 15 17:46:31 GMT 2023`
Record UNII	5AEV5C340C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OXELADIN CITRATE

Common Name

English

Oxeladin citrate [WHO-DD]

Common Name

English

2-(2-DIETHYLAMINOETHOXY)ETHYL 2-ETHYL-2-PHENYLBUTYRATE DIHYDROGEN CITRATE

Systematic Name

English

OXELADIN CITRATE [MI]

Common Name

English

NSC-759231

Code

English

OXELADIN CITRATE [MART.]

Common Name

English

OXELADIN DIHYDROGEN CITRATE

Common Name

English

OXELADIN HYDROGEN CITRATE [EP MONOGRAPH]

Common Name

English

OXELADIN CITRATE [JAN]

Common Name

English

OXELADIN HYDROGEN CITRATE

Common Name

English

OXELADINE CITRATE

Common Name

English

BENZENEACETIC ACID, .ALPHA.,.ALPHA.-DIETHYL-, 2-(2-(DIETHYLAMINO)ETHOXY)ETHYL ESTER, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1)

Systematic Name

English

Code System Code Type Description

CAS

52432-72-1