U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:22:03 GMT 2023
Edited
by admin
on Sat Dec 16 14:22:03 GMT 2023
Protein Type RECEPTOR
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
SG52LRE3BJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NEUROPILIN-1
Common Name English
VASCULAR ENDOTHELIAL CELL GROWTH FACTOR 165 RECEPTOR
Common Name English
CD_ANTIGEN: CD304
Common Name English
VEGF165R
Code English
NRP1
Code English
Code System Code Type Description
FDA UNII
SG52LRE3BJ
Created by admin on Sat Dec 16 14:22:03 GMT 2023 , Edited by admin on Sat Dec 16 14:22:03 GMT 2023
PRIMARY
UNIPROT
O14786
Created by admin on Sat Dec 16 14:22:03 GMT 2023 , Edited by admin on Sat Dec 16 14:22:03 GMT 2023
PRIMARY
From To
1_6 1_33
1_61 1_83
1_126 1_152
1_185 1_207
1_254 1_403
1_410 1_562
2_6 2_33
2_61 2_83
2_126 2_152
2_185 2_207
2_254 2_403
2_410 2_562
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_129
N 1_240
N 1_279
N 1_501
N 1_821
N 2_129
N 2_240
N 2_279
N 2_501
N 2_821
O 1_591
O 2_591
Related Record Type Details
ACTIVATOR -> TARGET
INHIBITOR -> TARGET
ACTIVATOR -> TARGET
Upon αV binding, a protease cleavage event is activated, revealing the c-terminal CendR motif (R/KXXR/K). The CendR motif is now able to bind to neuropilin-1, activating an endocytotic/exocytotic transport pathway
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL