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Details

Stereochemistry RACEMIC
Molecular Formula C17H17NO2
Molecular Weight 267.3224
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETAZEPINE

SMILES

CCOC1C2=C(C=CC=C2)N(C)C(=O)C3=C1C=CC=C3

InChI

InChIKey=BLGFGFHRMMDRPC-UHFFFAOYSA-N
InChI=1S/C17H17NO2/c1-3-20-16-12-8-4-5-9-13(12)17(19)18(2)15-11-7-6-10-14(15)16/h4-11,16H,3H2,1-2H3

HIDE SMILES / InChI
Molecular Formula C17H17NO2
Molecular Weight 267.3224
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Etazepine (5,6-dihydro-5-methyl-11H-11-ethoxy-dibenzo[b,e]azepin-6-one) demonstrates anticonvulsant activity in rodents. Etazepine seems to exert its anticonvulsant effects by activating the GABAergic system.

CNS Activity

CNS Active
4002
Curator's Comment: Etazepine is CNS active in animals. No human data available.

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Pharmacological profile of the new anticonvulsant etazepine.
1989-04
Patents

Patents

20100226943
186
6680047
81
WO2007061529A1
72
Substance Class Chemical
Created
by admin
on Wed Apr 02 09:30:34 GMT 2025
Edited
by admin
on Wed Apr 02 09:30:34 GMT 2025
Record UNII
SBC76K7XWC
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
etazepine [INN]
Preferred Name English
ETAZEPINE
INN  
INN  
Official Name English
(±)-11-ETHOXY-5,11-DIHYDRO-5-METHYL-6H-DIBENZ(B,E)AZEPIN-6-ONE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C264
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
Code System Code Type Description
INN
5533
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
EPA CompTox
DTXSID10868996
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
EVMPD
SUB07266MIG
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
WIKIPEDIA
Etazepine
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
CAS
88124-27-0
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
MESH
C060314
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
FDA UNII
SBC76K7XWC
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
SMS_ID
100000082391
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
NCI_THESAURUS
C65556
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
PUBCHEM
65662
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
ChEMBL
CHEMBL2106559
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
ECHA (EC/EINECS)
289-386-1
Created by admin on Wed Apr 02 09:30:34 GMT 2025 , Edited by admin on Wed Apr 02 09:30:34 GMT 2025
PRIMARY
Related Record Type Details
Structure of ETAZEPINE, (S)-
ENANTIOMER -> RACEMATE
Structure of ETAZEPINE, (R)-
ENANTIOMER -> RACEMATE
Related Record Type Details
Structure of ETAZEPINE
ACTIVE MOIETY
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