CLONITAZENE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H23ClN4O2
Molecular Weight	386.875
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

CCN(CC)CCN1C(CC2=CC=C(Cl)C=C2)=NC3=C1C=CC(=C3)[N+]([O-])=O

InChI

InChIKey=GPZLDQAEBHTMPG-UHFFFAOYSA-N

InChI=1S/C20H23ClN4O2/c1-3-23(4-2)11-12-24-19-10-9-17(25(26)27)14-18(19)22-20(24)13-15-5-7-16(21)8-6-15/h5-10,14H,3-4,11-13H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C20H23ClN4O2
Molecular Weight	386.875
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Clonitazene is a synthetic opioid analgesic, structurally related to etonitazene. In the USA clonitazene is a schedule I narcotic controlled substance.

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
opioid receptor activity 3	Activator 1,430

Patents

Patents

Substance Class	Chemical
Record UNII	S90R21A2V2
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

CLONITAZENE

Official Name

English

CLONITAZENE [MI]

Common Name

English

C-193901

Common Name

English

IDS-NC-002

Code

English

1H-BENZIMIDAZOLE-1-ETHANAMINE, 2-((4-CHLOROPHENYL)METHYL)-N,N-DIETHYL-5-NITRO-

Systematic Name

English

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Classification Tree

Code System

Code

Sedatives

WIKIPEDIA

Designer-drugs-Clonitazene

Sec. 1308.11 Schedule I.

DEA NO.

9612

Agent Affecting Nervous System

NCI_THESAURUS

C67413

Wikipedia

WIKIPEDIA

List_of_benzimidazole_opioids

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Code System

Code

Type

Description

FDA UNII

S90R21A2V2

PRIMARY

INN

1072

PRIMARY

EPA CompTox

DTXSID90191931

PRIMARY

EVMPD

SUB06731MIG

PRIMARY

ChEMBL

CHEMBL2104616

PRIMARY

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Related Record

Type

Details


					1PE72K8X46

MU-TYPE OPIOID RECEPTOR

TARGET -> AGONIST

Comments:

Emax=106 of Fentanyl

Qualification:

EC50

Amount:

140 NANOMOLAR [93.6 to 210] (average)


					WY482PZ9FK

CLONITAZENE METHYLSULFONATE

SALT/SOLVATE -> PARENT

Comments:

APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)

Amount:

RELATIONSHIP_AMOUNT 80 (average)


					GBN6Y8QR9G

CLONITAZENE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Comments:

APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)

Amount:

RELATIONSHIP_AMOUNT 91 (average)

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Related Record

Type

Details


					S90R21A2V2

CLONITAZENE

ACTIVE MOIETY

Amount:

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