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Details

Stereochemistry ABSOLUTE
Molecular Formula C4H5O6.Na.H2O
Molecular Weight 190.0839
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM BITARTRATE MONOHYDRATE

SMILES

O.[Na+].O[C@H]([C@@H](O)C([O-])=O)C(O)=O

InChI

InChIKey=LLVQEXSQFBTIRD-OLXYHTOASA-M
InChI=1S/C4H6O6.Na.H2O/c5-1(3(7)8)2(6)4(9)10;;/h1-2,5-6H,(H,7,8)(H,9,10);;1H2/q;+1;/p-1/t1-,2-;;/m1../s1

HIDE SMILES / InChI

Molecular Formula C4H6O6
Molecular Weight 150.0868
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Tartaric acid is found in many plants such as grapes, tamarinds, pineapples, mulberries and so on. Wine lees (called mud in the US), the sediment collected during the fermentation of grapes, contains potassium bitartrate (potassium hydrogen tartrate) as its major component. L-(+)-tartaric acid is an enantiomer of tartaric acid. Twenty five years before the tetrahedral structure for carbon was proposed in 1874 to explain the optical activity and other properties of organic compounds, Louis Pasteur discovered the existence of enantiomerism in tartaric acid. L-(+)-tartaric acid is widely used in food and beverage as acidity regulator with E number E334.

Originator

Curator's Comment: Scheele first prepared tartaric acid. Louis Pasteur discovered the existence of enantiomerism in tartaric acid

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
CLEARASIL DAILY CLEAR CLEAR SKIN

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Inhibition of leukotriene function can modulate particulate-induced changes in bone cell differentiation and activity.
2001
Vitreous concentration of topically applied brimonidine tartrate 0.2%.
2001 Apr
A novel and simplified route to the synthesis of N3S chelators for 99mTc labeling.
2001 Aug
Synthesis and evaluation of a C-glycosyl nucleoside as an inhibitor of chitin synthase.
2001 Aug 30
Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase.
2001 Dec
LAS, a novel selective estrogen receptor modulator with chemopreventive and therapeutic activity in the N-nitroso-N-methylurea-induced rat mammary tumor model.
2001 Dec 15
A comparison of salts for the crystallization of macromolecules.
2001 Feb
Response charactterization of ammonium tartrate solid state pellets for ESR dosimetry with radiotherapeutic photon and electron beams.
2001 Feb
Arsenic induces expression of the multidrug resistance-associated protein 2 (MRP2) gene in primary rat and human hepatocytes.
2001 Jul
A Mg-dependent ecto-ATPase in Leishmania amazonensis and its possible role in adenosine acquisition and virulence.
2001 Jul 1
Stability of chiral domains produced by adsorption of tartaric acid isomers on the Cu(110) surface: a periodic density functional theory study.
2001 Jul 11
Isolation and characterization of Mn(III) tartrate from Phanerochaete chrysosporium culture broth.
2001 Jul 24
Stabilization of minodronic acid in aqueous solution for parenteral formulation.
2001 Jul 3
Determination of organic acids of low molecular weight and phosphate in soil by capillary electrophoresis.
2001 Jul-Aug
Catalytic spectrophotometric determination of vanadium in seawaters based on the bromate oxidative coupling reaction of metol and 2,3,4-trihydroxybenzoic acid.
2001 Jun
Diverging respiratory effects of serotonin and nicotine in vagotomised cats prior to and after section of carotid sinus nerves.
2001 Mar
Crystal structure analysis and chiral recognition study of Delta-[Ru(bpy)2(py)2][(+)-O,O'-dibenzoylD-tartrate].12H2O and Lambda-[Ru(bpy)2(py)2][(-)-O,O'-dibenzoyl-L-tartrate].12H2O.
2001 Mar 12
[Increasing number of Salmonella paratyphi B isolates from slaughtered poultry sent in to the national Salmonella reference laboratory].
2001 May-Jun
[Acid phosphatase, ACP (EC 3.1.3.2)].
2001 Nov
Technetium-99m direct radiolabeling of lanreotide: a somatostatin analog.
2001 Nov
The hygroscopic properties of dicarboxylic and multifunctional acids: measurements and UNIFAC predictions.
2001 Nov 15
Direct chiral resolution of tartaric acid in food products by ligand exchange capillary electrophoresis using copper(II)-D-quinic acid as a chiral selector.
2001 Oct 12
Oxidation of hydroquinones by the versatile ligninolytic peroxidase from Pleurotus eryngii. H2O2 generation and the influence of Mn2+.
2001 Sep
Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines.
2001 Sep 15
Preformulation studies for an ultrashort-acting neuromuscular blocking agent GW280430A. I. Buffer and cosolvent effects on the solution stability.
2002
Acid phosphatases.
2002 Apr
The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.
2002 Apr
Towards atomic resolution with crystals grown in gel: the case of thaumatin seen at room temperature.
2002 Aug 1
Ergotamine-induced anorectal strictures: report of five cases.
2002 Feb
Diaquabis[mu-(R,R)-tartrato-kappa4O1,O2:O3,O4]dinickel(II) trihydrate.
2002 Feb
The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.
2002 Feb
Fibroblasts from the inner granulation tissue of the pseudocapsule in hips at revision arthroplasty induce osteoclast differentiation, as do stromal cells.
2002 Feb
Anaerobaculum mobile sp. nov., a novel anaerobic, moderately thermophilic, peptide-fermenting bacterium that uses crotonate as an electron acceptor, and emended description of the genus Anaerobaculum.
2002 Jan
Effect of antibiotics on in vitro and in vivo avian cartilage degradation.
2002 Jan-Mar
In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina.
2002 Jan-Mar
High frequency of phenotypic deviations in Physcomitrella patens plants transformed with a gene-disruption library.
2002 Jul 18
Boronic acid receptors for alpha-hydroxycarboxylates: high affinity of Shinkai's glucose receptor for tartrate.
2002 Jul 26
Improving the labeling of S-acetyl NHS-MAG(3)-conjugated morpholino oligomers.
2002 Jul-Aug
Effects of cyclic pressure on bone marrow cell cultures.
2002 Jun
Dissociation of angiogenesis and osteoclastogenesis during endochondral bone formation in neonatal mice.
2002 Jun
Stereoselective radical reactions of some tartaric and glyceric acid derivatives.
2002 Jun 13
Role of the Multidrug Resistance Protein 1 in protection from heavy metal oxyanions: investigations in vitro and in MRP1-deficient mice.
2002 Mar 1
Release of an acid phosphatase activity during lily pollen tube growth involves components of the secretory pathway.
2002 May
Synovial macrophage-osteoclast differentiation in inflammatory arthritis.
2002 Oct
Ectonucleotide diphosphohydrolase activity in Crithidia deanei.
2002 Oct
Formation of methylantimony species by an aerobic prokaryote: Flavobacterium sp.
2002 Oct
Development of high-affinity ligands and photoaffinity labels for the D-fructose transporter GLUT5.
2002 Oct 15
Symmetric and helical growth of polyacetylene fibers over a single copper crystal derived from copper tartrate decomposition.
2002 Sep 5
Patents

Sample Use Guides

L-(+)-tartaric acid as a food additive. Acceptable Daily Intake: 0-30 mg/kg
Route of Administration: Oral
In Vitro Use Guide
After incubation in medium containing 50 mM L(+)-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product.
Substance Class Chemical
Created
by admin
on Thu Jul 06 01:04:39 UTC 2023
Edited
by admin
on Thu Jul 06 01:04:39 UTC 2023
Record UNII
S66F32Y3ZO
Record Status Validated (UNII)
Record Version
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Name Type Language
SODIUM BITARTRATE MONOHYDRATE
MI  
Systematic Name English
SODIUM BITARTRATE MONOHYDRATE [MI]
Common Name English
SODIUM DITARTRATE HYDROGEN
Common Name English
SODIUM ACID TARTRATE MONOHYDRATE
Common Name English
TARTARIC ACID, MONOSODIUM SALT, MONOHYDRATE
Systematic Name English
BUTANEDIOIC ACID, 2,3-DIHYDROXY- (2R,3R)-, SODIUM SALT, HYDRATE (1:1:1)
Common Name English
Code System Code Type Description
MERCK INDEX
M9995
Created by admin on Thu Jul 06 01:04:39 UTC 2023 , Edited by admin on Thu Jul 06 01:04:39 UTC 2023
PRIMARY Merck Index
PUBCHEM
76965350
Created by admin on Thu Jul 06 01:04:39 UTC 2023 , Edited by admin on Thu Jul 06 01:04:39 UTC 2023
PRIMARY
CAS
6131-98-2
Created by admin on Thu Jul 06 01:04:39 UTC 2023 , Edited by admin on Thu Jul 06 01:04:39 UTC 2023
PRIMARY
EPA CompTox
DTXSID60635539
Created by admin on Thu Jul 06 01:04:39 UTC 2023 , Edited by admin on Thu Jul 06 01:04:39 UTC 2023
PRIMARY
FDA UNII
S66F32Y3ZO
Created by admin on Thu Jul 06 01:04:39 UTC 2023 , Edited by admin on Thu Jul 06 01:04:39 UTC 2023
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE
PARENT -> SALT/SOLVATE