Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C4H5O6.Na |
Molecular Weight | 172.0687 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].O[C@H]([C@@H](O)C([O-])=O)C(O)=O
InChI
InChIKey=NKAAEMMYHLFEFN-ZVGUSBNCSA-M
InChI=1S/C4H6O6.Na/c5-1(3(7)8)2(6)4(9)10;/h1-2,5-6H,(H,7,8)(H,9,10);/q;+1/p-1/t1-,2-;/m1./s1
Molecular Formula | Na |
Molecular Weight | 22.9898 |
Charge | 1 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C4H5O6 |
Molecular Weight | 149.0789 |
Charge | -1 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Tartaric acid is found in many plants such as grapes, tamarinds, pineapples, mulberries and so on. Wine lees (called mud in the US), the sediment collected during the fermentation of grapes, contains potassium bitartrate (potassium hydrogen tartrate) as its major component. L-(+)-tartaric acid is an enantiomer of tartaric acid. Twenty five years before the tetrahedral structure for carbon was proposed in 1874 to explain the optical activity and other properties of organic compounds, Louis Pasteur discovered the existence of enantiomerism in tartaric acid. L-(+)-tartaric acid is widely used in food and beverage as acidity regulator with E number E334.
Approval Year
PubMed
Title | Date | PubMed |
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Inhibition of leukotriene function can modulate particulate-induced changes in bone cell differentiation and activity. | 2001 |
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Studies on the association of 2-thiazolidinecarboxylic acid and antimony potassium tartrate: chiral recognition and prediction of absolute configuration by electrospray ionization mass spectrometry. | 2001 |
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Lasofoxifene (CP-336,156) protects against the age-related changes in bone mass, bone strength, and total serum cholesterol in intact aged male rats. | 2001 Apr |
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L-prolinium tartrate. | 2001 Apr |
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A comparison of salts for the crystallization of macromolecules. | 2001 Feb |
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Sarcosinium tartrate. | 2001 Feb |
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Entropy-controlled selectivity in the vinylation of a cyclic chiral nitrone. An efficient route to enantiopure polyhydroxylated pyrrolidines. | 2001 Feb 23 |
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Arsenic induces expression of the multidrug resistance-associated protein 2 (MRP2) gene in primary rat and human hepatocytes. | 2001 Jul |
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Stabilization of minodronic acid in aqueous solution for parenteral formulation. | 2001 Jul 3 |
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Dicaffeoyl- or digalloyl pyrrolidine and furan derivatives as HIV integrase inhibitors. | 2001 Jun |
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Classification of Ralstonia pickettii biovar 3/'thomasii' strains (Pickett 1994) and of new isolates related to nosocomial recurrent meningitis as Ralstonia mannitolytica sp. nov. | 2001 Mar |
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Crystal structure analysis and chiral recognition study of Delta-[Ru(bpy)2(py)2][(+)-O,O'-dibenzoylD-tartrate].12H2O and Lambda-[Ru(bpy)2(py)2][(-)-O,O'-dibenzoyl-L-tartrate].12H2O. | 2001 Mar 12 |
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Direct resolution of (+/-)-ephedrine and atropine into their enantiomers by impregnated TLC. | 2001 May |
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[Acid phosphatase, ACP (EC 3.1.3.2)]. | 2001 Nov |
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Platelet-activating factor modulates a secreted phosphatase activity of the trypanosomatid parasite Herpetomonas muscarum muscarum. | 2001 Oct |
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Direct chiral resolution of tartaric acid in food products by ligand exchange capillary electrophoresis using copper(II)-D-quinic acid as a chiral selector. | 2001 Oct 12 |
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Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines. | 2001 Sep 15 |
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Preformulation studies for an ultrashort-acting neuromuscular blocking agent GW280430A. I. Buffer and cosolvent effects on the solution stability. | 2002 |
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The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor. | 2002 Apr |
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Initial stages of cell-matrix adhesion can be mediated and modulated by cell-surface hyaluronan. | 2002 Apr |
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Chiral versus racemic building blocks in supramolecular chemistry: tartrate salts of organic diamines. | 2002 Apr |
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Towards atomic resolution with crystals grown in gel: the case of thaumatin seen at room temperature. | 2002 Aug 1 |
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Retention of anions on silica-based metalloporphyrin stationary phases. | 2002 Feb |
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The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter. | 2002 Feb |
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Fibroblasts from the inner granulation tissue of the pseudocapsule in hips at revision arthroplasty induce osteoclast differentiation, as do stromal cells. | 2002 Feb |
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Revision of absolute configuration of enantiomeric (methylenecyclopropyl)carbinols obtained from (R)-(-)- and (S)-(+)-epichlorohydrin and methylenetriphenylphosphorane. Implications for reaction mechanism and improved synthesis of antiviral methylenecyclopropane analogues of nucleosides. | 2002 Jan 11 |
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Effect of antibiotics on in vitro and in vivo avian cartilage degradation. | 2002 Jan-Mar |
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In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina. | 2002 Jan-Mar |
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High frequency of phenotypic deviations in Physcomitrella patens plants transformed with a gene-disruption library. | 2002 Jul 18 |
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Dissociation of angiogenesis and osteoclastogenesis during endochondral bone formation in neonatal mice. | 2002 Jun |
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Stereoselective radical reactions of some tartaric and glyceric acid derivatives. | 2002 Jun 13 |
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Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)2D3 response to short-term treatment with 1,25-dihydroxyvitamin D3 in vivo. | 2002 Jun 7 |
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Release of an acid phosphatase activity during lily pollen tube growth involves components of the secretory pathway. | 2002 May |
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Development of high-affinity ligands and photoaffinity labels for the D-fructose transporter GLUT5. | 2002 Oct 15 |
Sample Use Guides
L-(+)-tartaric acid as a food additive. Acceptable Daily Intake: 0-30 mg/kg
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3540104
After incubation in medium containing 50 mM L(+)-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product.
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:02:06 GMT 2023
by
admin
on
Fri Dec 15 15:02:06 GMT 2023
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Record UNII |
75E63I9H07
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Record Status |
Validated (UNII)
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Record Version |
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-
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JECFA EVALUATION |
INS-335(I)
Created by
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CFR |
21 CFR 331.11
Created by
admin on Fri Dec 15 15:02:06 GMT 2023 , Edited by admin on Fri Dec 15 15:02:06 GMT 2023
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CODEX ALIMENTARIUS (GSFA) |
INS-335(I)
Created by
admin on Fri Dec 15 15:02:06 GMT 2023 , Edited by admin on Fri Dec 15 15:02:06 GMT 2023
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CFR |
21 CFR 331.15
Created by
admin on Fri Dec 15 15:02:06 GMT 2023 , Edited by admin on Fri Dec 15 15:02:06 GMT 2023
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526-94-3
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75E63I9H07
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100000078102
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DTXSID70883423
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MONOSODIUM TARTRATE
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208-400-9
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m9995
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23684900
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SUB15273MIG
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89900
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PRIMARY | RxNorm |
Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE | |||
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SOLVATE->ANHYDROUS |