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Details

Stereochemistry ABSOLUTE
Molecular Formula C4H5O6.Na
Molecular Weight 172.0687
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM BITARTRATE

SMILES

[Na+].O[C@H]([C@@H](O)C([O-])=O)C(O)=O

InChI

InChIKey=NKAAEMMYHLFEFN-ZVGUSBNCSA-M
InChI=1S/C4H6O6.Na/c5-1(3(7)8)2(6)4(9)10;/h1-2,5-6H,(H,7,8)(H,9,10);/q;+1/p-1/t1-,2-;/m1./s1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C4H5O6
Molecular Weight 149.0789
Charge -1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Tartaric acid is found in many plants such as grapes, tamarinds, pineapples, mulberries and so on. Wine lees (called mud in the US), the sediment collected during the fermentation of grapes, contains potassium bitartrate (potassium hydrogen tartrate) as its major component. L-(+)-tartaric acid is an enantiomer of tartaric acid. Twenty five years before the tetrahedral structure for carbon was proposed in 1874 to explain the optical activity and other properties of organic compounds, Louis Pasteur discovered the existence of enantiomerism in tartaric acid. L-(+)-tartaric acid is widely used in food and beverage as acidity regulator with E number E334.

Originator

Curator's Comment: Scheele first prepared tartaric acid. Louis Pasteur discovered the existence of enantiomerism in tartaric acid

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
CLEARASIL DAILY CLEAR CLEAR SKIN

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Evaluation of bone metabolic markers in breast cancer with bone metastasis.
2001
Effect of brimonidine tartrate ophthalmic solution 0.2% on pupil size in normal eyes under different luminance conditions.
2001 Apr
A novel and simplified route to the synthesis of N3S chelators for 99mTc labeling.
2001 Aug
A comparison of salts for the crystallization of macromolecules.
2001 Feb
Identification of many crystal forms of Aspergillus nidulans dehydroquinate synthase.
2001 Feb
Entropy-controlled selectivity in the vinylation of a cyclic chiral nitrone. An efficient route to enantiopure polyhydroxylated pyrrolidines.
2001 Feb 23
Malo-ethanolic fermentation in grape must by recombinant strains of Saccharomyces cerevisiae.
2001 Jul
Arsenic induces expression of the multidrug resistance-associated protein 2 (MRP2) gene in primary rat and human hepatocytes.
2001 Jul
A Mg-dependent ecto-ATPase in Leishmania amazonensis and its possible role in adenosine acquisition and virulence.
2001 Jul 1
Determination of organic acids of low molecular weight and phosphate in soil by capillary electrophoresis.
2001 Jul-Aug
Dicaffeoyl- or digalloyl pyrrolidine and furan derivatives as HIV integrase inhibitors.
2001 Jun
Diverging respiratory effects of serotonin and nicotine in vagotomised cats prior to and after section of carotid sinus nerves.
2001 Mar
Classification of Ralstonia pickettii biovar 3/'thomasii' strains (Pickett 1994) and of new isolates related to nosocomial recurrent meningitis as Ralstonia mannitolytica sp. nov.
2001 Mar
Effect of several organic acids on phosphate adsorption by variable charge soils of central China.
2001 May
Direct resolution of (+/-)-ephedrine and atropine into their enantiomers by impregnated TLC.
2001 May
Production and characterization of 188Re-C595 antibody for radioimmunotherapy of transitional cell bladder cancer.
2001 May
Synthesis, characterization, and labeling with 99mTc/188Re of peptide conjugates containing a dithia-bisphosphine chelating agent.
2001 May-Jun
Platelet-activating factor modulates a secreted phosphatase activity of the trypanosomatid parasite Herpetomonas muscarum muscarum.
2001 Oct
Direct chiral resolution of tartaric acid in food products by ligand exchange capillary electrophoresis using copper(II)-D-quinic acid as a chiral selector.
2001 Oct 12
Oxidation of hydroquinones by the versatile ligninolytic peroxidase from Pleurotus eryngii. H2O2 generation and the influence of Mn2+.
2001 Sep
Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines.
2001 Sep 15
New materials for ESR dosimetry.
2002 Apr
Towards atomic resolution with crystals grown in gel: the case of thaumatin seen at room temperature.
2002 Aug 1
Diaquabis[mu-(R,R)-tartrato-kappa4O1,O2:O3,O4]dinickel(II) trihydrate.
2002 Feb
Fibroblasts from the inner granulation tissue of the pseudocapsule in hips at revision arthroplasty induce osteoclast differentiation, as do stromal cells.
2002 Feb
Engineering the substrate specificity of D-amino-acid oxidase.
2002 Jul 26
Stereoselective radical reactions of some tartaric and glyceric acid derivatives.
2002 Jun 13
Determination of the side-products formed during the nitroxide-mediated bleach oxidation of glucose to glucaric acid.
2002 Jun 5
Gender- and age-related differences in osteoclast formation from circulating precursors.
2002 Mar
Consumption of an omega-3 fatty acids product, INCELL AAFA, reduced side-effects of CPT-11 (irinotecan) in mice.
2002 Mar 18
Crystallization and preliminary X-ray crystallographic analysis of UDP-N-acetylglucosamine acyltransferase from Helicobacter pylori.
2002 May
Potassium antimonyl tartrate induces reactive oxygen species-related apoptosis in human myeloid leukemic HL60 cells.
2002 May
Synovial macrophage-osteoclast differentiation in inflammatory arthritis.
2002 Oct
Symmetric and helical growth of polyacetylene fibers over a single copper crystal derived from copper tartrate decomposition.
2002 Sep 5
Patents

Sample Use Guides

L-(+)-tartaric acid as a food additive. Acceptable Daily Intake: 0-30 mg/kg
Route of Administration: Oral
In Vitro Use Guide
After incubation in medium containing 50 mM L(+)-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product.
Substance Class Chemical
Created
by admin
on Wed Jul 05 22:34:09 UTC 2023
Edited
by admin
on Wed Jul 05 22:34:09 UTC 2023
Record UNII
75E63I9H07
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM BITARTRATE
II   MART.   MI   WHO-DD  
Systematic Name English
SODIUM BITARTRATE [MART.]
Common Name English
INS-335(I)
Code English
MONOBASIC SODIUM TARTRATE
Common Name English
E-335(I)
Code English
SODIUM HYDROGEN L-TARTRATE
Systematic Name English
Sodium bitartrate [WHO-DD]
Common Name English
MONOSODIUM TARTRATE
Systematic Name English
SODIUM BITARTRATE [II]
Common Name English
BUTANEDIOIC ACID, 2,3-DIHYDROXY- (2R,3R)-, MONOSODIUM SALT
Common Name English
INS NO.335(I)
Code English
MONOSODIUM L-(+)-TARTRATE
Systematic Name English
MONOSODIUM DL-TARTRATE
Common Name English
TARTARIC ACID, MONOSODIUM SALT
Common Name English
SODIUM BITARTRATE [MI]
Common Name English
SODIUM ACID TARTRATE
Common Name English
BUTANEDIOIC ACID, 2,3-DIHYDROXY- (2R,3R)-, SODIUM SALT (1:1)
Common Name English
SODIUM HYDROGEN TARTRATE
Systematic Name English
Classification Tree Code System Code
JECFA EVALUATION INS-335(I)
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
CFR 21 CFR 331.11
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
CODEX ALIMENTARIUS (GSFA) INS-335(I)
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
CFR 21 CFR 331.15
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
Code System Code Type Description
CAS
526-94-3
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
PRIMARY
FDA UNII
75E63I9H07
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
PRIMARY
SMS_ID
100000078102
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
PRIMARY
EPA CompTox
DTXSID70883423
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
PRIMARY
WIKIPEDIA
MONOSODIUM TARTRATE
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
PRIMARY
ECHA (EC/EINECS)
208-400-9
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
PRIMARY
MERCK INDEX
M9995
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
PRIMARY Merck Index
PUBCHEM
23684900
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
PRIMARY
EVMPD
SUB15273MIG
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
PRIMARY
RXCUI
89900
Created by admin on Wed Jul 05 22:34:09 UTC 2023 , Edited by admin on Wed Jul 05 22:34:09 UTC 2023
PRIMARY RxNorm
Related Record Type Details
PARENT -> SALT/SOLVATE
SOLVATE->ANHYDROUS