Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C4H5O6.Na |
Molecular Weight | 172.0687 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].O[C@H]([C@@H](O)C([O-])=O)C(O)=O
InChI
InChIKey=NKAAEMMYHLFEFN-ZVGUSBNCSA-M
InChI=1S/C4H6O6.Na/c5-1(3(7)8)2(6)4(9)10;/h1-2,5-6H,(H,7,8)(H,9,10);/q;+1/p-1/t1-,2-;/m1./s1
Molecular Formula | C4H5O6 |
Molecular Weight | 149.0789 |
Charge | -1 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Molecular Formula | Na |
Molecular Weight | 22.98976928 |
Charge | 1 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Tartaric acid is found in many plants such as grapes, tamarinds, pineapples, mulberries and so on. Wine lees (called mud in the US), the sediment collected during the fermentation of grapes, contains potassium bitartrate (potassium hydrogen tartrate) as its major component. L-(+)-tartaric acid is an enantiomer of tartaric acid. Twenty five years before the tetrahedral structure for carbon was proposed in 1874 to explain the optical activity and other properties of organic compounds, Louis Pasteur discovered the existence of enantiomerism in tartaric acid. L-(+)-tartaric acid is widely used in food and beverage as acidity regulator with E number E334.
Approval Year
Overview
CYP3A4 | CYP2C9 | CYP2D6 | hERG |
---|---|---|---|
OverviewOther
Other Inhibitor | Other Substrate | Other Inducer |
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Drug as perpetrator​
Target | Modality | Activity | Metabolite | Clinical evidence |
---|---|---|---|---|
no [IC50 >10 uM] | ||||
no [IC50 >10 uM] | ||||
no [IC50 >10 uM] | ||||
no [IC50 >10 uM] | ||||
no [IC50 >10 uM] | ||||
Page: 59.0 |
no | |||
yes [Ki 91 uM] |
Drug as victim
Target | Modality | Activity | Metabolite | Clinical evidence |
---|---|---|---|---|
yes | ||||
yes |
Tox targets
Target | Modality | Activity | Metabolite | Clinical evidence |
---|---|---|---|---|
Page: 93.0 |
PubMed
Title | Date | PubMed |
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Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin. | 2001 Jan |
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Capillary electrophoresis for evaluating orange juice authenticity: a study on Spanish oranges. | 2001 Jan |
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A Mg-dependent ecto-ATPase in Leishmania amazonensis and its possible role in adenosine acquisition and virulence. | 2001 Jul 1 |
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Catalytic spectrophotometric determination of vanadium in seawaters based on the bromate oxidative coupling reaction of metol and 2,3,4-trihydroxybenzoic acid. | 2001 Jun |
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Effect of several organic acids on phosphate adsorption by variable charge soils of central China. | 2001 May |
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Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport. | 2001 May 11 |
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[Increasing number of Salmonella paratyphi B isolates from slaughtered poultry sent in to the national Salmonella reference laboratory]. | 2001 May-Jun |
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Chemical and biochemical issues related to X-ray crystallography of the ligand-binding domain of estrogen receptor alpha. | 2001 May-Jun |
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The hygroscopic properties of dicarboxylic and multifunctional acids: measurements and UNIFAC predictions. | 2001 Nov 15 |
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Preformulation studies for an ultrashort-acting neuromuscular blocking agent GW280430A. I. Buffer and cosolvent effects on the solution stability. | 2002 |
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The MRP1-mediated effluxes of arsenic and antimony do not require arsenic-glutathione and antimony-glutathione complex formation. | 2002 Apr |
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New materials for ESR dosimetry. | 2002 Apr |
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Acid phosphatases. | 2002 Apr |
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The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor. | 2002 Apr |
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Stereoselective synthesis of myo-inositol via ring-closing metathesis: a building block for glycosylphosphatidylinositol (GPI) anchor synthesis. | 2002 Apr 18 |
|
Towards atomic resolution with crystals grown in gel: the case of thaumatin seen at room temperature. | 2002 Aug 1 |
|
Crystal structure analysis of the exocytosis-sensitive phosphoprotein, pp63/parafusin (phosphoglucomutase), from Paramecium reveals significant conformational variability. | 2002 Jan 11 |
|
A simple spectrophotometric method for the determination of copper in industrial, environmental, biological and soil samples using 2,5-dimercapto-1,3,4-thiadiazole. | 2002 Jul |
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High frequency of phenotypic deviations in Physcomitrella patens plants transformed with a gene-disruption library. | 2002 Jul 18 |
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Boronic acid receptors for alpha-hydroxycarboxylates: high affinity of Shinkai's glucose receptor for tartrate. | 2002 Jul 26 |
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Engineering the substrate specificity of D-amino-acid oxidase. | 2002 Jul 26 |
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Improving the labeling of S-acetyl NHS-MAG(3)-conjugated morpholino oligomers. | 2002 Jul-Aug |
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Effects of cyclic pressure on bone marrow cell cultures. | 2002 Jun |
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Dissociation of angiogenesis and osteoclastogenesis during endochondral bone formation in neonatal mice. | 2002 Jun |
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Stereoselective radical reactions of some tartaric and glyceric acid derivatives. | 2002 Jun 13 |
|
The separation of racemic crystals into enantiomers by chiral block copolymers. | 2002 Jun 3 |
|
Determination of the side-products formed during the nitroxide-mediated bleach oxidation of glucose to glucaric acid. | 2002 Jun 5 |
|
Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)2D3 response to short-term treatment with 1,25-dihydroxyvitamin D3 in vivo. | 2002 Jun 7 |
|
Consumption of an omega-3 fatty acids product, INCELL AAFA, reduced side-effects of CPT-11 (irinotecan) in mice. | 2002 Mar 18 |
|
Release of an acid phosphatase activity during lily pollen tube growth involves components of the secretory pathway. | 2002 May |
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Use of disposable GRC electrodes for the detection of phenol and chlorophenols in liquid chromatography. | 2002 May |
|
Crystallization and preliminary X-ray crystallographic analysis of UDP-N-acetylglucosamine acyltransferase from Helicobacter pylori. | 2002 May |
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Potassium antimonyl tartrate induces reactive oxygen species-related apoptosis in human myeloid leukemic HL60 cells. | 2002 May |
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Synovial macrophage-osteoclast differentiation in inflammatory arthritis. | 2002 Oct |
|
Ectonucleotide diphosphohydrolase activity in Crithidia deanei. | 2002 Oct |
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Formation of methylantimony species by an aerobic prokaryote: Flavobacterium sp. | 2002 Oct |
|
Effects of sigma(1) receptor ligand MS-377 on D(2) antagonists-induced behaviors. | 2002 Oct |
|
Development of high-affinity ligands and photoaffinity labels for the D-fructose transporter GLUT5. | 2002 Oct 15 |
|
Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator. | 2002 Oct 25 |
|
Symmetric and helical growth of polyacetylene fibers over a single copper crystal derived from copper tartrate decomposition. | 2002 Sep 5 |
Sample Use Guides
L-( )-tartaric acid as a food additive. Acceptable Daily Intake: 0-30 mg/kg
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3540104
After incubation in medium containing 50 mM L( )-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product.
Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 17:36:05 GMT 2025
by
admin
on
Mon Mar 31 17:36:05 GMT 2025
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Record UNII |
75E63I9H07
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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JECFA EVALUATION |
INS-335(I)
Created by
admin on Mon Mar 31 17:36:05 GMT 2025 , Edited by admin on Mon Mar 31 17:36:05 GMT 2025
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CFR |
21 CFR 331.11
Created by
admin on Mon Mar 31 17:36:05 GMT 2025 , Edited by admin on Mon Mar 31 17:36:05 GMT 2025
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CODEX ALIMENTARIUS (GSFA) |
INS-335(I)
Created by
admin on Mon Mar 31 17:36:05 GMT 2025 , Edited by admin on Mon Mar 31 17:36:05 GMT 2025
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CFR |
21 CFR 331.15
Created by
admin on Mon Mar 31 17:36:05 GMT 2025 , Edited by admin on Mon Mar 31 17:36:05 GMT 2025
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526-94-3
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75E63I9H07
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100000078102
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DTXSID70883423
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MONOSODIUM TARTRATE
Created by
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208-400-9
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m9995
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PRIMARY | Merck Index | ||
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23684900
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SUB15273MIG
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89900
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PRIMARY | RxNorm |
Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE | |||
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SOLVATE->ANHYDROUS |