TLY-012

Substance Class	Protein Created by `admin` on `Wed Apr 02 09:10:31 GMT 2025` Edited by `admin` on `Wed Apr 02 09:10:31 GMT 2025`
Protein Type	CYTOKINE
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	S4LKC378SN
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

TLY-012

Code

English

TLY012

Preferred Name

English

PEGYLATED RECOMBINANT HUMAN TUMOR NECROSIS FACTOR-RELATED APOPTOSIS INDUCING LIGAND

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

737920

Created by admin on Wed Apr 02 09:10:31 GMT 2025 , Edited by admin on Wed Apr 02 09:10:31 GMT 2025

Code System Code Type Description

FDA UNII

S4LKC378SN

Created by admin on Wed Apr 02 09:10:31 GMT 2025 , Edited by admin on Wed Apr 02 09:10:31 GMT 2025

PRIMARY

Related Record Type Details


					88N2PCJ6LG

PARENT -> DERIVATIVE

Amount:


					H8QG06RS7R

TARGET -> ACTIVATOR

Interaction Type:

IN-VITRO

Amount:

Related Record Type Details


					S4LKC378SN

TLY-012

ACTIVE MOIETY

Amount:

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
METAL_BINDING	[1_6] [1_13] [1_17] [1_24] [1_27] [1_31] [2_6] [2_10] [2_13] [2_17] [2_24] [2_27] [2_31] [3_6] [3_13] [3_17] [3_24] [3_27] [3_31]	SITE_SPECIFIC			ZINC CATION	13S1S8SF37
PEGYLATION		RESIDUE_SPECIFIC	LYSINE	Amount:	UNSPECIFIED SUBSTANCE	5f0be726 (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
ISOLEUCINE “ZIPPER” (ILZ)	PROTEIN FEATURE
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL