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Approval Year

Unknown
149124
Substance Class Structurally Diverse
Created
by admin
on Wed Apr 02 17:52:03 GMT 2025
Edited
by admin
on Wed Apr 02 17:52:03 GMT 2025
Source Materials Class ORGANISM
Source Materials Type ALLOGENIC HUMAN
Source Materials Parent
HOMO SAPIENS WHOLE
Part blood
Fraction Material Type cell
Fraction Name cd3- cells
Record UNII
S2RRP2SH5H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Nadravaleucel
USAN  
Official Name English
GDA-201
Preferred Name English
allogeneic natural killer (NK) cells isolated from peripheral blood leukapheresis of individual donors. The cells are co-cultured in media containing interleukin 15 (IL-15) and nicotinamide (NAM, niacinamide) with expansion enhanced by the presence of fe
Common Name English
NADRAVALEUCEL [USAN]
Common Name English
Code System Code Type Description
NCI_THESAURUS
C187130
Created by admin on Wed Apr 02 17:52:03 GMT 2025 , Edited by admin on Wed Apr 02 17:52:03 GMT 2025
PRIMARY
USAN
LM-191
Created by admin on Wed Apr 02 17:52:03 GMT 2025 , Edited by admin on Wed Apr 02 17:52:03 GMT 2025
PRIMARY
FDA UNII
S2RRP2SH5H
Created by admin on Wed Apr 02 17:52:03 GMT 2025 , Edited by admin on Wed Apr 02 17:52:03 GMT 2025
PRIMARY
SMS_ID
300000053867
Created by admin on Wed Apr 02 17:52:03 GMT 2025 , Edited by admin on Wed Apr 02 17:52:03 GMT 2025
PRIMARY
INN
12339
Created by admin on Wed Apr 02 17:52:03 GMT 2025 , Edited by admin on Wed Apr 02 17:52:03 GMT 2025
PRIMARY
Related Record Type Details
Nadravaleucel
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
CULTURE BIOLOGICAL MUROMONAB-CD3 JGA39ICE2V
CULTURE BIOLOGICAL NIACINAMIDE 25X51I8RD4
CULTURE BIOLOGICAL Glutamine 0RH81L854J
CULTURE BIOLOGICAL GENTAMICIN T6Z9V48IKG
CULTURE BIOLOGICAL HUMAN IL-15 HRJ300HC9W
CULTURE BIOLOGICAL HUMAN SERUM Z3R3JN730C
Name Property Type Amount Referenced Substance Defining Parameters References
ANTIGEN LOW EXPRESSION CHEMICAL
CD3
CD3
ANTIGEN EXPRESSED CHEMICAL
NEURAL CELL ADHESION MOLECULE 1
ANTIGEN EXPRESSED BIOLOGICAL
L-SELECTIN
ANTIGEN LOW EXPRESSION BIOLOGICAL
B-LYMPHOCYTE ANTIGEN CD19
ANTIGEN LOW EXPRESSION BIOLOGICAL
MONOCYTE DIFFERENTIATION ANTIGEN CD14
NIH
NCATS
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