U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 19:57:34 GMT 2023
Edited
by admin
on Sat Dec 16 19:57:34 GMT 2023
Source Materials Class ORGANISM
Source Materials Type ALLOGENIC HUMAN
Source Materials Parent
Part BLOOD
Fraction Material Type CELL
Fraction Name CD3- cells
Record UNII
S2RRP2SH5H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Nadravaleucel
USAN  
Official Name English
GDA-201
Code English
allogeneic natural killer (NK) cells isolated from peripheral blood leukapheresis of individual donors. The cells are co-cultured in media containing interleukin 15 (IL-15) and nicotinamide (NAM, niacinamide) with expansion enhanced by the presence of fe
Common Name English
NADRAVALEUCEL [USAN]
Common Name English
Code System Code Type Description
USAN
LM-191
Created by admin on Sat Dec 16 19:57:34 GMT 2023 , Edited by admin on Sat Dec 16 19:57:34 GMT 2023
PRIMARY
FDA UNII
S2RRP2SH5H
Created by admin on Sat Dec 16 19:57:34 GMT 2023 , Edited by admin on Sat Dec 16 19:57:34 GMT 2023
PRIMARY
INN
12339
Created by admin on Sat Dec 16 19:57:34 GMT 2023 , Edited by admin on Sat Dec 16 19:57:34 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
CULTURE BIOLOGICAL MUROMONAB-CD3 JGA39ICE2V
CULTURE BIOLOGICAL NIACINAMIDE 25X51I8RD4
CULTURE BIOLOGICAL GLUTAMINE 0RH81L854J
CULTURE BIOLOGICAL GENTAMICIN T6Z9V48IKG
CULTURE BIOLOGICAL HUMAN IL-15 HRJ300HC9W
CULTURE BIOLOGICAL HUMAN SERUM Z3R3JN730C
Name Property Type Amount Referenced Substance Defining Parameters References
ANTIGEN LOW EXPRESSION CHEMICAL
ANTIGEN EXPRESSED CHEMICAL
ANTIGEN EXPRESSED BIOLOGICAL
ANTIGEN LOW EXPRESSION BIOLOGICAL
ANTIGEN LOW EXPRESSION BIOLOGICAL