Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C36H62N4O2.4ClH |
| Molecular Weight | 728.747 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.Cl.Cl.COC1=CC=CC=C1CNCCCCCCNCCCCCCCCNCCCCCCNCC2=C(OC)C=CC=C2
InChI
InChIKey=CDKGGOUDHGSFAF-UHFFFAOYSA-N
InChI=1S/C36H62N4O2.4ClH/c1-41-35-23-13-11-21-33(35)31-39-29-19-9-7-17-27-37-25-15-5-3-4-6-16-26-38-28-18-8-10-20-30-40-32-34-22-12-14-24-36(34)42-2;;;;/h11-14,21-24,37-40H,3-10,15-20,25-32H2,1-2H3;4*1H
| Molecular Formula | C36H62N4O2 |
| Molecular Weight | 582.9031 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells. | 1989 Apr |
|
| Antagonist binding profiles of five cloned human muscarinic receptor subtypes. | 1991 Feb |
|
| Stimulation of cyclic AMP accumulation and phosphoinositide hydrolysis by M3 muscarinic receptors in the rat peripheral lung. | 1996 Aug 23 |
|
| Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. | 1997 Apr |
|
| Characterisation of [3H]-darifenacin as a novel radioligand for the study of muscarinic M3 receptors. | 1997 Jan-May |
|
| Pharmacological comparison of the cloned human and rat M2 muscarinic receptor genes expressed in the murine fibroblast (B82) cell line. | 1998 Feb |
|
| Constitutive activity and inverse agonism at the M2 muscarinic acetylcholine receptor. | 2006 Jan |
|
| Muscarinic acetylcholine receptor-dependent induction of persistent synaptic enhancement in rat hippocampus in vivo. | 2007 Jan 19 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:21:35 GMT 2023
by
admin
on
Sat Dec 16 08:21:35 GMT 2023
|
| Record UNII |
RLO2T99XT3
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
RLO2T99XT3
Created by
admin on Sat Dec 16 08:21:35 GMT 2023 , Edited by admin on Sat Dec 16 08:21:35 GMT 2023
|
PRIMARY | |||
|
Methoctramine
Created by
admin on Sat Dec 16 08:21:35 GMT 2023 , Edited by admin on Sat Dec 16 08:21:35 GMT 2023
|
PRIMARY | |||
|
107759
Created by
admin on Sat Dec 16 08:21:35 GMT 2023 , Edited by admin on Sat Dec 16 08:21:35 GMT 2023
|
PRIMARY | |||
|
73452
Created by
admin on Sat Dec 16 08:21:35 GMT 2023 , Edited by admin on Sat Dec 16 08:21:35 GMT 2023
|
PRIMARY | |||
|
104807-46-7
Created by
admin on Sat Dec 16 08:21:35 GMT 2023 , Edited by admin on Sat Dec 16 08:21:35 GMT 2023
|
PRIMARY | |||
|
DTXSID40146754
Created by
admin on Sat Dec 16 08:21:35 GMT 2023 , Edited by admin on Sat Dec 16 08:21:35 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
TARGET -> INHIBITOR |
Binding Assay
IC50
|
||
|
TARGET -> INHIBITOR |
methoctramine is a selective muscarinic M2 receptor antagonist
|
||
|
|
PARENT -> SALT/SOLVATE |
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
|