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Details

Stereochemistry RACEMIC
Molecular Formula C9H13NO3
Molecular Weight 183.2044
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NORDEFRIN

SMILES

C[C@H](N)[C@H](O)C1=CC=C(O)C(O)=C1

InChI

InChIKey=GEFQWZLICWMTKF-CDUCUWFYSA-N
InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1

HIDE SMILES / InChI

Molecular Formula C9H13NO3
Molecular Weight 183.2044
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Nordefrin is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor. Nordefrin is a racemic mixture of levo- and dextro- isomers and levonordefrin to be 100 to 200 times more active than dextro-nordefrin in raising blood pressure. Nordefrin is a structural isomer of epinephrine and levonordefrin produced a greater increase in heart rate than epinephrine.

Approval Year

PubMed

Substance Class Chemical
Record UNII
R81X549E70
Record Status Validated (UNII)
Record Version