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Details

Stereochemistry ACHIRAL
Molecular Formula C10H18N2O7
Molecular Weight 278.2591
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID

SMILES

OCCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

InChIKey=URDCARMUOSMFFI-UHFFFAOYSA-N
InChI=1S/C10H18N2O7/c13-4-3-11(5-8(14)15)1-2-12(6-9(16)17)7-10(18)19/h13H,1-7H2,(H,14,15)(H,16,17)(H,18,19)

HIDE SMILES / InChI

Molecular Formula C10H18N2O7
Molecular Weight 278.2591
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID (HEDTA) is used in cosmetics and care products. It’s a chelating agent, which in combination with selenium was effective in reducing the concentration of Al and level of DNA damage. In addition, experiments with rodents have shown that combination of HEDTA and propolis preserved histological features, mitigated oxidative stress and improved liver, kidney, and brain functions more profoundly.

Approval Year

PubMed

PubMed

TitleDatePubMed
Biodegradability of ethylenediamine-based complexing agents and related compounds.
2001 Aug
Inhibition of CaT1 channel activity by a noncompetitive IP3 antagonist.
2001 Jan 12
Biodegradability of ethylenediamine-based complexing agents.
2001 Jun
Beneficial effects of humic acid on micronutrient availability to wheat.
2001 Nov-Dec
Phytosiderophores influence on cadmium mobilization and uptake by wheat and barley plants.
2001 Nov-Dec
Determination of strong binding chelators and their metal complexes by anion-exchange chromatography and inductively coupled plasma mass spectrometry.
2002 Feb 22
On-column complexation and simultaneous separation of vanadium(IV) and vanadium(V) by capillary electrophoresis with direct UV detection.
2002 Oct
Effect of N-hydroxyethyl-ethylenediamine-triacetic acid (HEDTA) on Cr(VI) reduction by Fe(II).
2003 Jun
Preparation of Gd3+-containing polymer complex as a novel magnetic resonance signal-enhancing coating material.
2003 Mar
Isothermal titration calorimetric procedure to determine protein-metal ion binding parameters in the presence of excess metal ion or chelator.
2003 Mar 15
Biogeochemistry of fluoride in a plant-solution system.
2003 Nov-Dec
Light-catalyzed chromium(VI) reduction by organic compounds and soil minerals.
2003 Nov-Dec
Functional and structural study on chelator-induced suppression of S2/S1 FTIR spectrum in photosynthetic oxygen-evolving complex.
2003 Oct 1
Immobilization of Fe chelators on sepharose gel and its effect on their chemical properties.
2003 Sep 24
The excitation cascade of Limulus ventral photoreceptors: guanylate cyclase as the link between InsP3-mediated Ca2+ release and the opening of cGMP-gated channels.
2004 Feb 26
Separation of yttrium from heavy lanthanide by CA-100 using the complexing agent.
2004 May 28
The [Ru(Hedta)NO](0.1-) system: structure, chemical reactivity and biological assays.
2004 Nov
Equilibrium, kinetic and solvent effect studies on the reactions of [RuIII(Hedta)(H2O)] with thiols.
2005 Dec 21
Potential of Hemidesmus indicus for phytoextraction of lead from industrially contaminated soils.
2005 Jan
Neutrophil secretion induced by an intracellular Ca2+ rise and followed by whole-cell patch-clamp recordings occurs without any selective mobilization of different granule populations.
2006
Iron acquisition by phytosiderophores contributes to cadmium tolerance.
2007 Apr
Determination of alternative and conventional chelating agents as copper(II) complexes by capillary zone electrophoresis--the first use of didecyldimethylammonium bromide as a flow reversal reagent.
2007 Feb 12
Confirmation of vanadium complex formation using electrospray mass spectrometry and determination of vanadium speciation by sample stacking capillary electrophoresis.
2007 Feb 28
Determination of synthetic ferric chelates used as fertilizers by liquid chromatography-electrospray/mass spectrometry in agricultural matrices.
2007 Jan
A dendrite-autonomous mechanism for direction selectivity in retinal starburst amacrine cells.
2007 Jul
Influence of soil type on the mobility and bioavailability of chelated zinc.
2007 May 2
Homeostatic control of slow vacuolar channels by luminal cations and evaluation of the channel-mediated tonoplast Ca2+ fluxes in situ.
2008
Kosmotropes enhance the yield of antibody purified by affinity chromatography using immobilized bacterial immunoglobulin binding proteins.
2008
Poly[μ-aqua-diaqua-(μ(3)-N'-carboxy-methyl-ethylenediamine-N,N,N'-tri-acetato)oxidopotassium(I)vanadium(IV)].
2008 Jun 7
A novel manganese complex effective as superoxide anion scavenger and therapeutic agent against cell and tissue oxidative injury.
2009 Nov 26
Development of a novel aluminum tolerance phenotyping platform used for comparisons of cereal aluminum tolerance and investigations into rice aluminum tolerance mechanisms.
2010 Aug
Spatial distribution of calcium-gated chloride channels in olfactory cilia.
2010 Dec 30
Poly[[[μ(3)-N'-(carboxymethyl)ethylene-di-amine-N,N,N'-triacetato]dysprosium(III)] trihydrate].
2010 Oct 23
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:02:04 GMT 2023
Edited
by admin
on Fri Dec 15 15:02:04 GMT 2023
Record UNII
R79J91U341
Record Status Validated (UNII)
Record Version
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Name Type Language
HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID
HSDB  
Common Name English
HEDTA
INCI  
INCI  
Official Name English
N-HYDROXYETHYL ETHYLENEDIAMINE TRIACETIC ACID
Systematic Name English
HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID [HSDB]
Common Name English
HEDTA [INCI]
Common Name English
N-(2-HYDROXYETHYL)ETHYLENEDIAMINETRIACETIC ACID
Common Name English
NSC-7341
Code English
N-(2-HYDROXYETHYL)ETHYLENEDIAMINE-N,N',N'-TRIACETIC ACID
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 39108
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
Code System Code Type Description
NSC
7341
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
PRIMARY
HSDB
5651
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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RXCUI
1364568
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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DAILYMED
R79J91U341
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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CAS
150-39-0
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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FDA UNII
R79J91U341
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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MESH
C026060
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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PUBCHEM
8773
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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EPA CompTox
DTXSID1059737
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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ECHA (EC/EINECS)
205-759-3
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
PRIMARY
WIKIPEDIA
Hydroxyethylethylenediaminetriacetic acid
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
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ACTIVE MOIETY