U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:10:56 GMT 2023
Edited
by admin
on Sat Dec 16 13:10:56 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
QOG25L6Z8Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SPARTALIZUMAB
INN  
Official Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PROGRAMMED CELL DEATH PROTEIN 1 (PROTEIN PD-1, CD-279 ANTIGEN))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.4 HEAVY CHAIN (1-443) (HUMANIZED VH (HOMO SAPIENS IGHV1-69-2*01 (75%) (IGHD)-IGHJ6*01) (8.8.10) (1-117)-HOMO SA
Systematic Name English
PDR-001
Code English
IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1)(HUMAN-MUS MUSCULUS MONOCLONAL CLONE NVS240118 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL CLONE NVS240118 .KAPPA.-CHAIN, DIMER
Systematic Name English
NVP-LZV184
Code English
SPARTALIZUMAB [JAN]
Common Name English
SPARTALIZUMAB [USAN]
Common Name English
spartalizumab [INN]
Common Name English
Spartalizumab [WHO-DD]
Common Name English
PDR001
Code English
ANTI-PD1 MONOCLONAL ANTIBODY PDR001
Code English
Classification Tree Code System Code
NCI_THESAURUS C129822
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
FDA ORPHAN DRUG 653418
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
NCI_THESAURUS C128037
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
FDA ORPHAN DRUG 819321
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
FDA ORPHAN DRUG 576417
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
Code System Code Type Description
CAS
1935694-88-4
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
PRIMARY
INN
10624
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
PRIMARY
NCI_THESAURUS
C121625
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
PRIMARY
DRUG BANK
DB14892
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
PRIMARY
USAN
GH-36
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
PRIMARY
FDA UNII
QOG25L6Z8Z
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
PRIMARY
WIKIPEDIA
Spartalizumab
Created by admin on Sat Dec 16 13:10:56 GMT 2023 , Edited by admin on Sat Dec 16 13:10:56 GMT 2023
PRIMARY
From To
1_22 1_96
1_131 3_220
1_144 1_200
1_223 2_223
1_226 2_226
1_258 1_318
1_364 1_422
2_22 2_96
2_131 4_220
2_144 2_200
2_258 2_318
2_364 2_422
3_23 3_94
3_140 3_200
4_23 4_94
4_140 4_200
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_294
N 2_294
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL