Details
Stereochemistry | ACHIRAL |
Molecular Formula | C7H8O3S |
Molecular Weight | 172.202 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=C(C=C1)S(O)(=O)=O
InChI
InChIKey=JOXIMZWYDAKGHI-UHFFFAOYSA-N
InChI=1S/C7H8O3S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H,8,9,10)
Molecular Formula | C7H8O3S |
Molecular Weight | 172.202 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
p-Toluenesulfonic acid (PTSA) is an organic compound with the formula CH3C6H4SO3H. An aromatic sulfonic acid, often used as a strong acid catalyst. p-Toluenesulfonic acid monohydrate has been used as a reducing agent for the reductive amination of ketones and aldehydes. In the presence of p-Toluenesulfonic acid monohydrate novel deazaflavin-cholestane hybrid compounds have been synthesized in a condensation reaction. 2-Phenylethyl alpha-glucoside has also been synthesized in the presence of p-Toluenesulfonic acid monohydrate. p-toluenesulfonic acid esters, are a common class of reagents used in the pharmaceutical
industry as alkylating agents, catalysts, and in purification steps of the chemical synthesis of a drug substance.
Approval Year
PubMed
Title | Date | PubMed |
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Preparation of 1,2-O-isopropylidene derivatives of alpha-D-galactoseptanose, beta-L-altroseptanose, and 3-O-methyl-alpha-D-guloseptanose. | 2001 Aug 23 |
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Anion binding with two polyammonium macrocycles of different dimensionality. | 2001 Aug 27 |
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Anion allosteric effect in the recognition of tetramethylammonium salts by calix[4]arene cone conformers. | 2001 Dec 14 |
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[7alpha-18F]fluoro-17alpha-methyl-5alpha-dihydrotestosterone: a ligand for androgen receptor-mediated imaging of prostate cancer. | 2001 Jan |
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[Cytokine production by peripheral blood mononuclear cells in bronchial asthma treated with suplatast tosilate]. | 2001 Jun |
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Modification of eosinophil function by suplatast tosilate (IPD), a novel anti-allergic drug. | 2001 Nov |
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Microwave induced synthesis of ribonucleosides on solid support. | 2002 |
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Exclusive and complete introduction of amino groups and their N-sulfo and N-carboxymethyl groups into the 6-position of cellulose without the use of protecting groups. | 2002 Aug 16 |
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Anion effects on the recognition of ion pairs by calix[4]arene-based heteroditopic receptors. | 2002 Aug 23 |
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Synthesis and antiviral activity of novel exomethylene cyclopropyl pyrimidine nucleosides. | 2002 Dec |
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Application of micellar electrokinetic chromatography to the determination of sultamicillin in oral pharmaceutical preparations. | 2002 Dec 6 |
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Tetra-N-confused cyclohexapyrrole: the unusual product formed by condensation of 3,3'-dipyrromethane with tripyrrin-aldehyde. | 2002 Jul 12 |
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Acid catalyzed transesterification as a route to poly(3-hydroxybutyrate-co-epsilon-caprolactone) copolymers from their homopolymers. | 2002 Jul-Aug |
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Metal ion-dependent molecular inclusion chemistry: inclusion of aromatic anions by coordinated 1,4,7,10-tetrakis((S)-2-hydroxy-3-phenoxypropyl)-1,4,7,10-tetraazacyclododecane. | 2002 Mar 11 |
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Suppression of the Th2 pathway by suplatast tosilate in patients with perennial nasal allergies. | 2002 Nov-Dec |
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Sonolysis of surfactants in aqueous solutions: an accumulation of solute in the interfacial region of the cavitation bubbles. | 2002 Sep |
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Effects of suplatast tosilate on cytokine profile of bronchoalveolar cells in allergic inflammation of the lung. | 2002 Sep |
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Deoxygenation of carbohydrates by thiol-catalysed radical-chain redox rearrangement of the derived benzylidene acetals. | 2003 Apr 21 |
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Reaction of imidazole with toluene-4-sulfonate salts of substituted phenyl N-methylpyridinium-4-carboxylate esters: special base catalysis by imidazole. | 2003 Jun 7 |
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An additional regulator, TsaQ, is involved with TsaR in regulation of transport during the degradation of p-toluenesulfonate in Comamonas testosteroni T-2. | 2003 Nov |
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Thiyl radical reaction with thymine: absolute rate constant for hydrogen abstraction and comparison to benzylic C-H bonds. | 2003 Sep |
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Ruthenium complexes with chiral tetradentate imino-sulfoxide ligands. | 2003 Sep 22 |
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Synthesis and cytotoxicity of 9-(2-deoxy-2-alkyldithio-beta-D-arabinofuranosyl)purine nucleosides which are stable precursors to potential mechanistic probes of ribonucleotide reductases. | 2004 Jan 7 |
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Raman spectroscopy of benzenesulfonic and 4-toluenesulfonic acids dissolved in dimethylsulfoxide. | 2004 Jun |
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Application of ionic liquid halide nucleophilicity for the cleavage of ethers: a green protocol for the regeneration of phenols from ethers. | 2004 May 14 |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: http://www.sciencelab.com/msds.php?msdsId=9927004
Rat: Acute toxicity at 2570 mg/kg
Route of Administration:
Oral
Substance Class |
Chemical
Created
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admin
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Fri Dec 15 15:46:02 GMT 2023
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Fri Dec 15 15:46:02 GMT 2023
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Record UNII |
QGV5ZG5741
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Validated (UNII)
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EPA PESTICIDE CODE |
79058
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m10962
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DB03120
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P-TOLUENESULFONIC ACID
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Related Record | Type | Details | ||
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PARENT -> CONSTITUENT ALWAYS PRESENT | |||
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SOLVATE->ANHYDROUS |
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SALT/SOLVATE -> PARENT |
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PARENT -> IMPURITY |
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
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