Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H8O3S.H2O |
| Molecular Weight | 190.217 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.CC1=CC=C(C=C1)S(O)(=O)=O
InChI
InChIKey=KJIFKLIQANRMOU-UHFFFAOYSA-N
InChI=1S/C7H8O3S.H2O/c1-6-2-4-7(5-3-6)11(8,9)10;/h2-5H,1H3,(H,8,9,10);1H2
| Molecular Formula | C7H8O3S |
| Molecular Weight | 172.202 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
p-Toluenesulfonic acid (PTSA) is an organic compound with the formula CH3C6H4SO3H. An aromatic sulfonic acid, often used as a strong acid catalyst. p-Toluenesulfonic acid monohydrate has been used as a reducing agent for the reductive amination of ketones and aldehydes. In the presence of p-Toluenesulfonic acid monohydrate novel deazaflavin-cholestane hybrid compounds have been synthesized in a condensation reaction. 2-Phenylethyl alpha-glucoside has also been synthesized in the presence of p-Toluenesulfonic acid monohydrate. p-toluenesulfonic acid esters, are a common class of reagents used in the pharmaceutical
industry as alkylating agents, catalysts, and in purification steps of the chemical synthesis of a drug substance.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Anion effects on the recognition of ion pairs by calix[4]arene-based heteroditopic receptors. | 2002 Aug 23 |
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| Tandem Pummerer/Mannich cyclization cascade of alpha-sulfinylamides as a method to prepare aza-heterocycles. | 2002 Aug 23 |
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| Suplatast tosilate inhibits thymus- and activation-regulated chemokine production by antigen-specific human Th2 cells. | 2002 Dec |
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| [Unexpected formation of an estrone derivative from androsta-1,4-diene-3,17-dione]. | 2002 Dec |
|
| Synthesis and antiviral activity of novel exomethylene cyclopropyl pyrimidine nucleosides. | 2002 Dec |
|
| Bimetallic carbonyl thiolates as functional models for Fe-only hydrogenases. | 2002 Dec 16 |
|
| Application of micellar electrokinetic chromatography to the determination of sultamicillin in oral pharmaceutical preparations. | 2002 Dec 6 |
|
| Role of spin trapping and P2Y receptor antagonism in the neuroprotective effects of 2,2'-pyridylisatogen tosylate and related compounds. | 2002 May 24 |
|
| A fully automated one pot synthesis of 9-(4-[18F]fluoro-3-hydroxymethylbutyl) guanine for gene therapy studies. | 2002 Nov |
|
| Synthesis and evaluation of no-carrier-added 8-cyclopentyl-3-(3-[(18)F]fluoropropyl)-1-propylxanthine ([(18)F]CPFPX): a potent and selective A(1)-adenosine receptor antagonist for in vivo imaging. | 2002 Nov 7 |
|
| Suppression of the Th2 pathway by suplatast tosilate in patients with perennial nasal allergies. | 2002 Nov-Dec |
|
| Importance of the nature of anions in lysozyme crystallisation correlated with protein net charge variation. | 2002 Oct |
|
| Sonolysis of surfactants in aqueous solutions: an accumulation of solute in the interfacial region of the cavitation bubbles. | 2002 Sep |
|
| Synthesis and anticonvulsant activity of some new dioxolane derivatives. | 2003 |
|
| Deoxygenation of carbohydrates by thiol-catalysed radical-chain redox rearrangement of the derived benzylidene acetals. | 2003 Apr 21 |
|
| Novel oxidative alpha-tosyloxylation of alcohols with iodosylbenzene and p-toluenesulfonic acid and its synthetic use for direct preparation of heteroaromatics. | 2003 Aug 8 |
|
| Total synthesis of (+/-)-kainic Acid with an aza-[2,3]-Wittig sigmatropic rearrangement as the key stereochemical determining step. | 2003 Aug 8 |
|
| Synthesis, structure, and screening of estrogenic and antiestrogenic activity of new 3,17-substituted-16,17-seco-estratriene derivatives. | 2003 Dec |
|
| Molecular recognition of alkylammonium contact ion-pairs using a ditopic receptor. | 2003 Dec 12 |
|
| Solid-state structure dependence of the molecular distortion and spectroscopic properties of the Cu(I) bis(2,9-dimethyl-1,10-phenanthroline) ion. | 2003 Dec 29 |
|
| A complete family of isostructural cluster compounds with cubane-like M(3)S(4)M' cores (M = Mo, W; M' = Ni, Pd, Pt): comparative crystallography and electrochemistry. | 2003 Feb 24 |
|
| Total synthesis of (-)-pironetin. | 2003 Feb 6 |
|
| Antineoplastic agents 500. Narcistatin. | 2003 Jan |
|
| Oxidative addition of aryl tosylates to palladium(0) and coupling of unactivated aryl tosylates at room temperature. | 2003 Jul 23 |
|
| [Methanogenic sarcina from an anaerobic microbial community degrading p-toluene sulfonate]. | 2003 Jul-Aug |
|
| Reaction of imidazole with toluene-4-sulfonate salts of substituted phenyl N-methylpyridinium-4-carboxylate esters: special base catalysis by imidazole. | 2003 Jun 7 |
|
| [New photosensitizers of bacteriochlorin series for photodynamic cancer therapy]. | 2003 Mar-Apr |
|
| Phasing power at the K absorption edge of organic arsenic. | 2003 May |
|
| Effects of suplatast tosilate on allergic eosinophilic airway inflammation in patients with mild asthma. | 2003 May |
|
| Improved synthesis of pure [18F]fluoro-compounds for PET studies from bromo-compounds. | 2003 May |
|
| Antibacterial characteristics of newly developed amphiphilic lipids and DNA-lipid complexes against bacteria. | 2003 May 1 |
|
| A study on the conversion of indanones into carbostyrils. | 2003 May 15 |
|
| Chirality control in 2,2'-biphosphole ligand leading to enantiopure Pd complex. | 2003 May 21 |
|
| An additional regulator, TsaQ, is involved with TsaR in regulation of transport during the degradation of p-toluenesulfonate in Comamonas testosteroni T-2. | 2003 Nov |
|
| Cytotoxic activity of tropolones against human oral tumor cell lines. | 2003 Nov-Dec |
|
| [Analysis of the anaerobic microbial community capable of degrading p-toluene sulphonate]. | 2003 Nov-Dec |
|
| Generating diverse skeletons of small molecules combinatorially. | 2003 Oct 24 |
|
| Convenient preparation of L-arabino-hexos-5-ulose derivatives from lactose. | 2003 Oct 31 |
|
| A novel synthesis of acyclonucleosides via allylation of 3-[1-(phenylhydrazono)-L-threo-2,3,4-trihydroxybut-1-yl]quinoxalin-2(1H)one. | 2003 Oct 31 |
|
| Thiyl radical reaction with thymine: absolute rate constant for hydrogen abstraction and comparison to benzylic C-H bonds. | 2003 Sep |
|
| Ruthenium complexes with chiral tetradentate imino-sulfoxide ligands. | 2003 Sep 22 |
|
| A sequential Pummerer-Diels-Alder route for the generation and trapping of furo[3,4-c]pyridines: synthesis of heterocyclic analogues of 1-arylnaphthalene lignans. | 2003 Sep 5 |
|
| Cyclodextrin complexation of a stilbene and the self-assembly of a simple molecular device. | 2004 Feb 7 |
|
| Synthesis and cytotoxicity of 9-(2-deoxy-2-alkyldithio-beta-D-arabinofuranosyl)purine nucleosides which are stable precursors to potential mechanistic probes of ribonucleotide reductases. | 2004 Jan 7 |
|
| Solid-phase synthesis of a library of hydroxyproline derivatives. | 2004 Jan-Feb |
|
| Conjugation of amino-containing drugs to polysaccharides by tosylation: amphotericin B-arabinogalactan conjugates. | 2004 Jul |
|
| Raman spectroscopy of benzenesulfonic and 4-toluenesulfonic acids dissolved in dimethylsulfoxide. | 2004 Jun |
|
| Application of ionic liquid halide nucleophilicity for the cleavage of ethers: a green protocol for the regeneration of phenols from ethers. | 2004 May 14 |
|
| Synthesis of the new, cubane-like W3S4Co cluster core. Completion of the homologous series [(eta5-Cp')3M3S4Co(CO)] (M = Cr, Mo, W). | 2004 May 31 |
|
| Intercalation behavior and tensile strength of DNA-lipid films for the dental application. | 2004 Nov |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 01:46:53 GMT 2023
by
admin
on
Sat Dec 16 01:46:53 GMT 2023
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| Record UNII |
3BTO78GAFF
|
| Record Status |
Validated (UNII)
|
| Record Version |
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6192-52-5
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3BTO78GAFF
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DTXSID5044316
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m10962
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521998
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C029501
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| Related Record | Type | Details | ||
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ANHYDROUS->SOLVATE |
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