| Stereochemistry | ABSOLUTE |
| Molecular Formula | C5H9NO4 |
| Molecular Weight | 147.1293 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
N[C@H](CCC(O)=O)C(O)=O
InChI
InChIKey=WHUUTDBJXJRKMK-GSVOUGTGSA-N
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
| Molecular Formula | C5H9NO4 |
| Molecular Weight | 147.1293 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. D-glutamate has been detected in blood, saliva, and urine, and trace quantities have been detected in mammalian tissues. Recently was found, that mitochondrial D-glutamate cyclase converts D-glutamate to 5-oxo-D-proline.
Originator
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
PubMed
Patents
Sample Use Guides
500 ml water plus 2 g (13.3 mmol) of D-glutamate was ingested within a 20-min period 1 h after a light breakfast (coffee, toast, and juice).
Route of Administration:
Oral
To investigate roles of 9030617O03Rik in D-glutamate metabolism, it was analyzed enzyme activity using cloned and purified the 9030617O03Rik protein. Following the purification of recombinant 9030617O03Rik, D-glutamate (10 mM as a substrate) degradation activity was confirmed. The in vitro enzyme assay showed no glutamate racemase activity or D-glutamate oxidase activity of the protein.
