U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 14:26:54 GMT 2023
Edited
by admin
on Sat Dec 16 14:26:54 GMT 2023
Nucleic Acid Type RNAI
Nucleic Acid Subtype
Sequence Type COMPLETE
Record UNII
P3CNL1GL6K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LIXADESIRAN
INN  
Official Name English
STP-705 COMPONENT ANTI-COX2 SI-RNA FREE ACID
Common Name English
lixadesiran [INN]
Common Name English
RNA, (A-C-A-U-C-A-U-C-A-G-A-C-C-A-G-G-C-A-C-C-A-G-A-C-C), COMPLEX WITH RNA (G-G-U-C-U-G-G-U-G-C-C-U-G-G-U-C-U-G-A-U-G-A-U-G-U) (1:1)
Common Name English
Code System Code Type Description
NCI_THESAURUS
C184815
Created by admin on Sat Dec 16 14:26:55 GMT 2023 , Edited by admin on Sat Dec 16 14:26:55 GMT 2023
PRIMARY
CAS
1152798-49-6
Created by admin on Sat Dec 16 14:26:55 GMT 2023 , Edited by admin on Sat Dec 16 14:26:55 GMT 2023
PRIMARY
FDA UNII
P3CNL1GL6K
Created by admin on Sat Dec 16 14:26:55 GMT 2023 , Edited by admin on Sat Dec 16 14:26:55 GMT 2023
PRIMARY
INN
11757
Created by admin on Sat Dec 16 14:26:55 GMT 2023 , Edited by admin on Sat Dec 16 14:26:55 GMT 2023
PRIMARY
Sugar Site Range Site Count
D-Ribose (RNA) 1_1-1_25;2_1-2_25 50 / 50
Linkage Site Range Site Count
Phosphate 1_2-1_25;2_2-2_25 48 / 48
Related Record Type Details
SALT/SOLVATE -> PARENT
TARGET->INHIBITOR OF EXPRESSION
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL