Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C32H32F2N4O6 |
| Molecular Weight | 606.6165 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@@H](NC(=O)C(C)(F)F)[C@@H](OC1=CC=C2N(N=CC2=C1)C3=CC(=CC=C3)C(=O)N[C@@H]4CCOC4)C5=CC=C6OCCOC6=C5
InChI
InChIKey=ZZWJKLGCDHYVMB-XGBAOLAVSA-N
InChI=1S/C32H32F2N4O6/c1-19(36-31(40)32(2,33)34)29(20-6-9-27-28(16-20)43-13-12-42-27)44-25-7-8-26-22(15-25)17-35-38(26)24-5-3-4-21(14-24)30(39)37-23-10-11-41-18-23/h3-9,14-17,19,23,29H,10-13,18H2,1-2H3,(H,36,40)(H,37,39)/t19-,23-,29-/m1/s1
| Molecular Formula | C32H32F2N4O6 |
| Molecular Weight | 606.6165 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 11:02:31 UTC 2023
by
admin
on
Sat Dec 16 11:02:31 UTC 2023
|
| Record UNII |
P30N0911C2
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Official Name | English | ||
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Code | English | ||
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Common Name | English | ||
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Systematic Name | English | ||
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Common Name | English | ||
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Code | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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300000010809
Created by
admin on Sat Dec 16 11:02:32 UTC 2023 , Edited by admin on Sat Dec 16 11:02:32 UTC 2023
|
PRIMARY | |||
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11103
Created by
admin on Sat Dec 16 11:02:32 UTC 2023 , Edited by admin on Sat Dec 16 11:02:32 UTC 2023
|
PRIMARY | |||
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HI-159
Created by
admin on Sat Dec 16 11:02:32 UTC 2023 , Edited by admin on Sat Dec 16 11:02:32 UTC 2023
|
PRIMARY | |||
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P30N0911C2
Created by
admin on Sat Dec 16 11:02:32 UTC 2023 , Edited by admin on Sat Dec 16 11:02:32 UTC 2023
|
PRIMARY | |||
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139593415
Created by
admin on Sat Dec 16 11:02:32 UTC 2023 , Edited by admin on Sat Dec 16 11:02:32 UTC 2023
|
PRIMARY | |||
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1196509-60-0
Created by
admin on Sat Dec 16 11:02:32 UTC 2023 , Edited by admin on Sat Dec 16 11:02:32 UTC 2023
|
PRIMARY | |||
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C171915
Created by
admin on Sat Dec 16 11:02:32 UTC 2023 , Edited by admin on Sat Dec 16 11:02:32 UTC 2023
|
PRIMARY |
| Related Record | Type | Details | ||
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TARGET -> AGONIST |
Transrepression activity (TR), assessed as the inhibition of AP-1-mediated transcription. Efficacy, maximum response relative to Dexamethasone (100%)=107%
IC50
|
||
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TARGET -> AGONIST |
LPS-induced TNF-α release in peripheral blood mononuclear cells. Efficacy, maximum response relative to Dexamethasone (100%)=75%
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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