FODIPIR

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H32N4O14P2
Molecular Weight	638.4554
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=NC=C(COP(O)(O)=O)C(CN(CCN(CC(O)=O)CC2=C(O)C(C)=NC=C2COP(O)(O)=O)CC(O)=O)=C1O

InChI

InChIKey=SQKUFYLUXROIFM-UHFFFAOYSA-N

InChI=1S/C22H32N4O14P2/c1-13-21(31)17(15(5-23-13)11-39-41(33,34)35)7-25(9-19(27)28)3-4-26(10-20(29)30)8-18-16(12-40-42(36,37)38)6-24-14(2)22(18)32/h5-6,31-32H,3-4,7-12H2,1-2H3,(H,27,28)(H,29,30)(H2,33,34,35)(H2,36,37,38)

HIDE SMILES / InChI

Molecular Formula	C22H32N4O14P2
Molecular Weight	638.4554
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Detection of malignant primary hepatic neoplasms with gadobenate dimeglumine (Gd-BOPTA) enhanced T1-weighted hepatocyte phase MR imaging: results of off-site blinded review in a phase-II multicenter trial.	2001 Oct-Dec	11754328
[Organ specific MRI contrast media in general practice].	2002	12621828
Contrast-enhanced MRI of the liver with mangafodipir trisodium: imaging technique and results.	2002 Mar-Apr	11884777
Improved image contrast with mangafodipir trisodium (MnDPDP) during MR-guided percutaneous cryosurgery of the liver.	2003 Jul	12915191
Antioxidant activity of mangafodipir is not a new finding.	2004 May	15094242
Detection and characterization of focal hepatic lesions: mangafodipir vs. superparamagnetic iron oxide-enhanced magnetic resonance imaging.	2004 Oct	15390224
Ultrasound of living donor liver transplantation.	2006 Apr	21614227
MR contrast agents for liver imaging: what, when, how.	2006 Nov-Dec	17102040
[Contrast-enhanced magnetic resonance cholangiography using gadolinium-EOB-DTPA. Preliminary experience and clinical applications].	2007 Jun	17965849
Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis.	2009 Oct	19834427
Prevention of 7β-hydroxycholesterol-induced cell death by mangafodipir is mediated through lysosomal and mitochondrial pathways.	2010 Aug 25	20452343

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:28:42 UTC 2023` Edited by `admin` on `Fri Dec 15 15:28:42 UTC 2023`
Record UNII	P28BIW0UTB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FODIPIR

Official Name

English

FODIPIR [USAN]

Common Name

English

DPDP

Code

English

fodipir [INN]

Common Name

English

GLYCINE, N,N'-1,2-ETHANEDIYLBIS(N-((3-HYDROXY-2-METHYL-5-((PHOSPHONOOXY)METHYL)-4-PYRIDINYL)METHYL)-

Systematic Name

English

N,N'-1,2-ETHANEDIYLBIS(N-((3-HYDROXY-2-METHYL-5-((PHOSPHONOOXY)METHYL)-4-PYRIDINYL)METHYL)GLYCINE)

Systematic Name

English

Code System Code Type Description

EVMPD

SUB07772MIG