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Approval Year

Unknown
134361
Substance Class Protein
Created
by admin
on Thu Jul 06 19:03:39 UTC 2023
Edited
by admin
on Thu Jul 06 19:03:39 UTC 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
OYN3CCI6QE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TIRZEPATIDE
USAN   INN  
Official Name English
LY3298176
Code English
LY-3298176
Code English
TIRZEPATIDE [USAN]
Common Name English
L-TYROSYL-2-METHYLALANYL-L-.ALPHA.-GLUTAMYLGLYCYL-L-THREONYL-L-PHENYLALANYL-L-THREONYL-L-SERYL-L- .ALPHA.-ASPARTYL-L-TYROSYL-L-SERYL-L-ISOLEUCYL-2-METHYLALANYL-L-LEUCYL-L-.ALPHA.-ASPARTYL-L-LYSYL-LISOLEUCYL- L-ALANYL-L-GLUTAMINYL-N6-((22S)-22,42-DICARBOX
Systematic Name English
Mounjaro
Brand Name English
L-SERINAMIDE,L-TYROSYL-2-METHYLALANYL-L-.ALPHA.-GLUTAMYLGLYCYL-L-THREONYL-L-PHENYLALANYL-LTHREONYL- L-SERYL-L-.ALPHA.-ASPARTYL-L-TYROSYL-L-SERYL-L-ISOLEUCYL-2-METHYLALANYL-L-LEUCYL-L-.ALPHA.- ASPARTYL-L-LYSYL-L-ISOLEUCYL-L-ALANYL-L-GLUTAMINYL-N6-((22S)-2
Systematic Name English
TIRZEPATIDE [JAN]
Common Name English
Tirzepatide [WHO-DD]
Common Name English
tirzepatide [INN]
Common Name English
Code System Code Type Description
USAN
EF-81
Created by admin on Thu Jul 06 19:03:39 UTC 2023 , Edited by admin on Thu Jul 06 19:03:39 UTC 2023
PRIMARY
FDA UNII
OYN3CCI6QE
Created by admin on Thu Jul 06 19:03:39 UTC 2023 , Edited by admin on Thu Jul 06 19:03:39 UTC 2023
PRIMARY
DAILYMED
OYN3CCI6QE
Created by admin on Thu Jul 06 19:03:39 UTC 2023 , Edited by admin on Thu Jul 06 19:03:39 UTC 2023
PRIMARY
INN
10849
Created by admin on Thu Jul 06 19:03:39 UTC 2023 , Edited by admin on Thu Jul 06 19:03:39 UTC 2023
PRIMARY
WIKIPEDIA
Tirzepatide
Created by admin on Thu Jul 06 19:03:39 UTC 2023 , Edited by admin on Thu Jul 06 19:03:39 UTC 2023
PRIMARY
CAS
2023788-19-2
Created by admin on Thu Jul 06 19:03:39 UTC 2023 , Edited by admin on Thu Jul 06 19:03:39 UTC 2023
PRIMARY
NCI_THESAURUS
C174817
Created by admin on Thu Jul 06 19:03:39 UTC 2023 , Edited by admin on Thu Jul 06 19:03:39 UTC 2023
PRIMARY
DRUG BANK
DB15171
Created by admin on Thu Jul 06 19:03:39 UTC 2023 , Edited by admin on Thu Jul 06 19:03:39 UTC 2023
PRIMARY
RXCUI
2601723
Created by admin on Thu Jul 06 19:03:39 UTC 2023 , Edited by admin on Thu Jul 06 19:03:39 UTC 2023
PRIMARY
Related Record Type Details
GLUCAGON-LIKE PEPTIDE 1 RECEPTOR
TARGET->PARTIAL AGONIST
On GLP-1R, TZP is a partial agonist 51% stimulation. shows bias towards cAMP (a messenger associated with regulation of glycogen, sugar and lipid metabolism) generation, rather than β-arrestin recruitment.
EC50
GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR
TARGET -> AGONIST
GTPγS binding of Gαs in GIPR versus GIP(1-42) of 1.43 nM
EC50
Related Record Type Details
TIRZEPATIDE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:SEQUENCE(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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