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Approval Year

2022
358
Substance Class Protein
Created
by admin
on Sat Dec 16 13:24:27 UTC 2023
Edited
by admin
on Sat Dec 16 13:24:27 UTC 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
OYN3CCI6QE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Tirzepatide
USAN   INN  
Official Name English
LY3298176
Code English
LY-3298176
Code English
TIRZEPATIDE [USAN]
Common Name English
L-Tyrosyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-2-methylalanyl-L-leucyl-L-α-aspartyl-L-lysyl-L-isoleucyl-L-alanyl-L-glutaminyl-N6-[(22S)-22,42-dicarboxy-1,10,19,24-tet
Systematic Name English
MOUNJARO
Brand Name English
L-Serinamide, L-tyrosyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-2-methylalanyl-L-leucyl-L-α-aspartyl-L-lysyl-L-isoleucyl-L-alanyl-L-glutaminyl-N6-[(22S)-22,42-dicarboxy-
Systematic Name English
TIRZEPATIDE [JAN]
Common Name English
Tirzepatide [WHO-DD]
Common Name English
tirzepatide [INN]
Common Name English
BG-121
Code English
ZEPBOUND
Brand Name English
Code System Code Type Description
USAN
EF-81
Created by admin on Sat Dec 16 13:24:27 UTC 2023 , Edited by admin on Sat Dec 16 13:24:27 UTC 2023
PRIMARY
FDA UNII
OYN3CCI6QE
Created by admin on Sat Dec 16 13:24:27 UTC 2023 , Edited by admin on Sat Dec 16 13:24:27 UTC 2023
PRIMARY
DAILYMED
OYN3CCI6QE
Created by admin on Sat Dec 16 13:24:27 UTC 2023 , Edited by admin on Sat Dec 16 13:24:27 UTC 2023
PRIMARY
INN
10849
Created by admin on Sat Dec 16 13:24:27 UTC 2023 , Edited by admin on Sat Dec 16 13:24:27 UTC 2023
PRIMARY
WIKIPEDIA
Tirzepatide
Created by admin on Sat Dec 16 13:24:27 UTC 2023 , Edited by admin on Sat Dec 16 13:24:27 UTC 2023
PRIMARY
CAS
2023788-19-2
Created by admin on Sat Dec 16 13:24:27 UTC 2023 , Edited by admin on Sat Dec 16 13:24:27 UTC 2023
PRIMARY
NCI_THESAURUS
C174817
Created by admin on Sat Dec 16 13:24:27 UTC 2023 , Edited by admin on Sat Dec 16 13:24:27 UTC 2023
PRIMARY
DRUG BANK
DB15171
Created by admin on Sat Dec 16 13:24:27 UTC 2023 , Edited by admin on Sat Dec 16 13:24:27 UTC 2023
PRIMARY
RXCUI
2601723
Created by admin on Sat Dec 16 13:24:27 UTC 2023 , Edited by admin on Sat Dec 16 13:24:27 UTC 2023
PRIMARY
Related Record Type Details
GLUCAGON-LIKE PEPTIDE 1 RECEPTOR
TARGET->PARTIAL AGONIST
On GLP-1R, TZP is a partial agonist 51% stimulation. shows bias towards cAMP (a messenger associated with regulation of glycogen, sugar and lipid metabolism) generation, rather than β-arrestin recruitment.
EC50
GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR
TARGET -> AGONIST
GTPγS binding of Gαs in GIPR versus GIP(1-42) of 1.43 nM
EC50
Related Record Type Details
Tirzepatide
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:SEQUENCE(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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