Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C20H21NOS2 |
| Molecular Weight | 355.517 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@H](NCC=C(C1=CSC=C1)C2=CSC=C2)[C@H](O)C3=CC=CC=C3
InChI
InChIKey=JQSHEDRVRBSFCZ-YWZLYKJASA-N
InChI=1S/C20H21NOS2/c1-15(20(22)16-5-3-2-4-6-16)21-10-7-19(17-8-11-23-13-17)18-9-12-24-14-18/h2-9,11-15,20-22H,10H2,1H3/t15-,20-/m0/s1
| Molecular Formula | C20H21NOS2 |
| Molecular Weight | 355.517 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Tinofedrine is a dithienylamine derivative patented by Deutsche Gold- und Silber-Scheideanstalt vorm. Roessler for improvement of cerebral and peripheral blood flow. In anesthetized dogs, Tinofedrine causes a remarkable increase of cardiac output by positive inotropic and chronotropic stimulation of the heart and simultaneous reduction of peripheral vascular resistance. In comparison with typical beta-agonists Tinofedrine at isotropically equieffective doses, has a much weaker effect on the heart rate. In coronary circulation, Tinofedrine causes vasodilation so that in a therapeutic dose range increased workload is equalized by sufficient myocardial supply.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:46:38 GMT 2023
by
admin
on
Fri Dec 15 15:46:38 GMT 2023
|
| Record UNII |
OVJ0W8F17T
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
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Official Name | English | ||
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Systematic Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C87053
Created by
admin on Fri Dec 15 15:46:38 GMT 2023 , Edited by admin on Fri Dec 15 15:46:38 GMT 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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3843
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66788-41-8
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CHEMBL2105422
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DTXSID00216907
Created by
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266-477-4
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100000077208
Created by
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PRIMARY | |||
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OVJ0W8F17T
Created by
admin on Fri Dec 15 15:46:38 GMT 2023 , Edited by admin on Fri Dec 15 15:46:38 GMT 2023
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C018159
Created by
admin on Fri Dec 15 15:46:38 GMT 2023 , Edited by admin on Fri Dec 15 15:46:38 GMT 2023
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PRIMARY | |||
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m498
Created by
admin on Fri Dec 15 15:46:38 GMT 2023 , Edited by admin on Fri Dec 15 15:46:38 GMT 2023
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PRIMARY | Merck Index | ||
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3666
Created by
admin on Fri Dec 15 15:46:38 GMT 2023 , Edited by admin on Fri Dec 15 15:46:38 GMT 2023
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C90634
Created by
admin on Fri Dec 15 15:46:38 GMT 2023 , Edited by admin on Fri Dec 15 15:46:38 GMT 2023
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PRIMARY | |||
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SUB11076MIG
Created by
admin on Fri Dec 15 15:46:38 GMT 2023 , Edited by admin on Fri Dec 15 15:46:38 GMT 2023
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PRIMARY | |||
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3033341
Created by
admin on Fri Dec 15 15:46:38 GMT 2023 , Edited by admin on Fri Dec 15 15:46:38 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
