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Details

Stereochemistry ACHIRAL
Molecular Formula C16H19NO2.C4H4O4
Molecular Weight 373.3997
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of MEDIFOXAMINE FUMARATE

SMILES

OC(=O)\C=C\C(O)=O.CN(C)CC(OC1=CC=CC=C1)OC2=CC=CC=C2

InChI

InChIKey=CSQUJXBMSDQIKM-WLHGVMLRSA-N
InChI=1S/C16H19NO2.C4H4O4/c1-17(2)13-16(18-14-9-5-3-6-10-14)19-15-11-7-4-8-12-15;5-3(6)1-2-4(7)8/h3-12,16H,13H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

HIDE SMILES / InChI

Molecular Formula C4H4O4
Molecular Weight 116.0722
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Molecular Formula C16H19NO2
Molecular Weight 257.3276
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Medifoxamine, an antidepressive drug, preferentially inhibits dopamine reuptake. It was marketed in France, but because of the hepatotoxicity, then was withdrawn.

Approval Year

PubMed

PubMed

TitleDatePubMed

Sample Use Guides

After an overnight fast, ascending doses of 200, 500, 750 and 1000 mg of medifoxamine were taken orally
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:36:56 UTC 2023
Edited
by admin
on Fri Dec 15 15:36:56 UTC 2023
Record UNII
OAG6T7TVU2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MEDIFOXAMINE FUMARATE
MI   WHO-DD  
Common Name English
MEDIFOXAMINE FUMARATE [MI]
Common Name English
GERAXYL
Brand Name English
ACETALDEHYDE, (DIMETHYLAMINO)-, DIPHENYL ACETAL, FUMARATE (1:1)
Common Name English
LG 152
Code English
N,N-DIMETHYL-N-(2,2-DIPHENOXYETHYL)AMINE FUMARATE
Systematic Name English
Medifoxamine fumarate [WHO-DD]
Common Name English
LG-152
Code English
CLEDIAL
Brand Name English
ETHANAMINE, N,N-DIMETHYL-2,2-DIPHENOXY-, (2E)-2-BUTENEDIOATE (1:1)
Systematic Name English
ETHANAMINE, N,N-DIMETHYL-2,2-DIPHENOXY-, (E)-2-BUTENEDIOATE (1:1)
Systematic Name English
Code System Code Type Description
MESH
C034065
Created by admin on Fri Dec 15 15:36:56 UTC 2023 , Edited by admin on Fri Dec 15 15:36:56 UTC 2023
PRIMARY
PUBCHEM
6450232
Created by admin on Fri Dec 15 15:36:56 UTC 2023 , Edited by admin on Fri Dec 15 15:36:56 UTC 2023
PRIMARY
RXCUI
236781
Created by admin on Fri Dec 15 15:36:56 UTC 2023 , Edited by admin on Fri Dec 15 15:36:56 UTC 2023
PRIMARY RxNorm
ECHA (EC/EINECS)
240-657-2
Created by admin on Fri Dec 15 15:36:56 UTC 2023 , Edited by admin on Fri Dec 15 15:36:56 UTC 2023
PRIMARY
MERCK INDEX
m7131
Created by admin on Fri Dec 15 15:36:56 UTC 2023 , Edited by admin on Fri Dec 15 15:36:56 UTC 2023
PRIMARY Merck Index
FDA UNII
OAG6T7TVU2
Created by admin on Fri Dec 15 15:36:56 UTC 2023 , Edited by admin on Fri Dec 15 15:36:56 UTC 2023
PRIMARY
CAS
16604-45-8
Created by admin on Fri Dec 15 15:36:56 UTC 2023 , Edited by admin on Fri Dec 15 15:36:56 UTC 2023
PRIMARY
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ACTIVE MOIETY