MEDIFOXAMINE FUMARATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H19NO2.C4H4O4
Molecular Weight	373.3997
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)\C=C\C(O)=O.CN(C)CC(OC1=CC=CC=C1)OC2=CC=CC=C2

InChI

InChIKey=CSQUJXBMSDQIKM-WLHGVMLRSA-N

InChI=1S/C16H19NO2.C4H4O4/c1-17(2)13-16(18-14-9-5-3-6-10-14)19-15-11-7-4-8-12-15;5-3(6)1-2-4(7)8/h3-12,16H,13H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

HIDE SMILES / InChI

Molecular Formula	C4H4O4
Molecular Weight	116.0722
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Molecular Formula	C16H19NO2
Molecular Weight	257.3276
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: | https://www.ncbi.nlm.nih.gov/pubmed/12506267 | https://www.ncbi.nlm.nih.gov/pubmed/7114665

Medifoxamine, an antidepressive drug, preferentially inhibits dopamine reuptake. It was marketed in France, but because of the hepatotoxicity, then was withdrawn.

Approval Year

PubMed

Title	Date	PubMed

Sample Use Guides

In Vivo Use Guide

After an overnight fast, ascending doses of 200, 500, 750 and 1000 mg of medifoxamine were taken orally

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:36:56 GMT 2023` Edited by `admin` on `Fri Dec 15 15:36:56 GMT 2023`
Record UNII	OAG6T7TVU2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MEDIFOXAMINE FUMARATE

Common Name

English

MEDIFOXAMINE FUMARATE [MI]

Common Name

English

GERAXYL

Brand Name

English

ACETALDEHYDE, (DIMETHYLAMINO)-, DIPHENYL ACETAL, FUMARATE (1:1)

Common Name

English

LG 152

Code

English

N,N-DIMETHYL-N-(2,2-DIPHENOXYETHYL)AMINE FUMARATE

Systematic Name

English

Medifoxamine fumarate [WHO-DD]

Common Name

English

LG-152

Code

English

CLEDIAL

Brand Name

English

ETHANAMINE, N,N-DIMETHYL-2,2-DIPHENOXY-, (2E)-2-BUTENEDIOATE (1:1)

Systematic Name

English

ETHANAMINE, N,N-DIMETHYL-2,2-DIPHENOXY-, (E)-2-BUTENEDIOATE (1:1)

Systematic Name

English

Code System Code Type Description

MESH

C034065