MEDIFOXAMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H19NO2
Molecular Weight	257.3276
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MEDIFOXAMINE

Structure Search

SMILES

CN(C)CC(OC1=CC=CC=C1)OC2=CC=CC=C2

InChI

InChIKey=QNMGHBMGNRQPNL-UHFFFAOYSA-N

InChI=1S/C16H19NO2/c1-17(2)13-16(18-14-9-5-3-6-10-14)19-15-11-7-4-8-12-15/h3-12,16H,13H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C16H19NO2
Molecular Weight	257.3276
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: | https://www.ncbi.nlm.nih.gov/pubmed/12506267 | https://www.ncbi.nlm.nih.gov/pubmed/7114665

Medifoxamine, an antidepressive drug, preferentially inhibits dopamine reuptake. It was marketed in France, but because of the hepatotoxicity, then was withdrawn.

Approval Year

PubMed

PubMed

Title	Date	PubMed

Sample Use Guides

In Vivo Use Guide

After an overnight fast, ascending doses of 200, 500, 750 and 1000 mg of medifoxamine were taken orally

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:47:22 GMT 2023` Edited by `admin` on `Fri Dec 15 16:47:22 GMT 2023`
Record UNII	KWU7C2A1NT
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MEDIFOXAMINE

Official Name

English

medifoxamine [INN]

Common Name

English

Medifoxamine [WHO-DD]

Common Name

English

MEDIFOXAMINE [MI]

Common Name

English

MEDIFOXAMINE [MART.]

Common Name

English

(DIMETHYLAMINO)ACETALDEHYDE DIPHENYL ACETAL

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66884

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

NCI_THESAURUS

C47794

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

WHO-VATC

QN06AX13

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

WHO-ATC

N06AX13

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

Code System Code Type Description

WIKIPEDIA

MEDIFOXAMINE

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

PUBCHEM

36109

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

SMS_ID

100000081990

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

RXCUI

29434

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

RxNorm

MERCK INDEX

m7131

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

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Merck Index

DRUG CENTRAL

1656

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

ChEMBL

CHEMBL85231

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

FDA UNII

KWU7C2A1NT

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

MESH

C034065

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

ECHA (EC/EINECS)

251-011-4

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

CAS

32359-34-5

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

INN

3759

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

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EPA CompTox

DTXSID80186078

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

DRUG BANK

DB13219

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

NCI_THESAURUS

C83914

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

EVMPD

SUB08693MIG

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

Related Record Type Details


					OAG6T7TVU2

MEDIFOXAMINE FUMARATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					KWU7C2A1NT

ACTIVE MOIETY