DIMETHOLIZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H24N2O2
Molecular Weight	264.3633
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COCCCN1CCN(CC1)C2=CC=CC=C2OC

InChI

InChIKey=ITNSQDCAZVVFMS-UHFFFAOYSA-N

InChI=1S/C15H24N2O2/c1-18-13-5-8-16-9-11-17(12-10-16)14-6-3-4-7-15(14)19-2/h3-4,6-7H,5,8-13H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C15H24N2O2
Molecular Weight	264.3633
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 431, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | https://www.ncbi.nlm.nih.gov/pubmed/23826885 | https://www.ncbi.nlm.nih.gov/pubmed/19881490

Dimetholizine has antihypertensive activity. It is an antihistaminic agent too. Histamine H1 receptor was predicted as a primary target for dimetholizine. Moreover, it was found to bind the Dopamine D2 and 5-HT1A receptors. Dimetholizine was predicted to be alpha1D-Adrenergic blocker.

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:22:00 GMT 2023` Edited by `admin` on `Fri Dec 15 16:22:00 GMT 2023`
Record UNII	O6U9W3DMYT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIMETHOLIZINE

Official Name

English

1-(O-METHOXYPHENYL)-4-(3-METHOXYPROPYL)PIPERAZINE

Common Name

English

dimetholizine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578